Top 300 Flashcards
What is the brand name of CLARITHROMYCIN (Antibiotic/Macrolide)
Biaxin
What is the indication for clarithromycin?
Infectious disease (bacterial)
What are the CI/warnings for clarithromycin?
use with ergot derivatives, pimozide, cisapride, astemizole, terfenadine, colchicine, lovastatin, simvastatin; history of cholestatic jaundice or hepatic dysfunction with prior clarithromycin use; history of QT prolongation or ventricular arrhythmia
What are the primary AE’s of clarithromycin?
abdominal pain, nausea, vomiting, dysguesia Warnings: pregancy, hepatotoxicity, CYP3A4 interactions, CDAD
What is the brand name for CLINDAMYCIN HCL (Antibiotic/Lincosamide)?
Cleocin
What is the indication for clindamycin?
Infectious disease (bacterial)
What is the BBW for clindamycin?
Can cause severe and possibly fatal colitis
What are the primary AE’s of clindamycin?
nausea, vomiting, diarrhea, rash Warnings: CDAD
What is the brand name for DOXYCYCLINE HYCLAT (Antibiotic/Tetracycline)?
Doryx (tab), Doxy 100 (IV), Vibramycin (susp, syrup, cap)
What is the indication for doxycycline?
Infectious disease (bacterial)
What are the primary AE’s of doxycycline?
anorexia, nausea, vomiting, esophageal irritation/ulceration Warnings: Teeth discoloration (pregnancy, children < 8 y), CDAD, photosensitivity, bacterial overgrowth, intracranial hypertension
What is the brand name for ERYTHROMYCIN (Antibiotic/Macrolide)?
E.E.S., Erypred (susp), Ery-tab, Erythrocin
What is the indication for erythromycin?
Infectious disease (bacterial)
What are the CI/warnings for erythromycin?
Concurrent use with ergotamine or dihydroergotamine, terfenadine, astemizole, lovastatin, or simvastatin
What are the primary AE’s of erythromycin?
nausea, vomiting, abdominal pain, diarrhea, anorexia Warnings: hepatotoxicity, QT prolongation, CDAD, CYP3A4 interactions
What is the brand name for LEVOFLOXACIN (Antibiotic/Fluroquinolone)?
Levaquin
What is the indication for levofloxacin?
Infectious disease (bacterial)
What is the BBW for levofloxacin?
Tendon rupture, worsening myasthenia gravis
What are the primary AE’s of levofloxacin?
diarrhea, nausea, vomiting, crystalluria, headache, dizziness Warnings: hypersensitivity, hepatotoxicity, CNS effects, CDAD, peripheral neuropathy, QT prolongation, blood glucose disturbances, photosensitivity, bacterial resistance
What is the brand name for METRONIDAZOLE (Antibiotic/Nitroimidazole)?
Flagyl
What is the indication for metronidazole?
Infectious disease (bacterial)
What is the BBW for metronidazole?
Possible carcinogenic
What are the CI/warnings for metronidazole?
Pregnancy (1st trimester), use of alcohol during therapy
What are the primary AE’s of metronidazole?
nausea, headache, abdominal cramping, metallic tase, furry tongue, glossitis, neutropenia, Warnings: encephalopathy, peripheral neuropathy, aseptic meningitis, seizures
What is the brand name for NITROFURANTOIN MONOHYDRATE / MACROCRYSTALLINE (Antibiotic)?
Macrobid
What is the indication for nitrofurantoin?
Infectious disease (bacterial)
What are the CI/warnings for nitrofurantoin?
Pregnancy at term, anuria, significant renal impairment, significant cholestatic jaundice with prior use
What are the primary AE’s of nitrofurantoin?
nausea, headache, flatulance Warnings: pulmonary pneumonitis / fibrosis, hepatotoxicity, neuropathy, hemolytic anemia, CDAD
What is the brand name for PENICILLIN VK (Antibiotic/Penicillin)?
Truxicillin VK
What is the indication for penicillin?
Infectious disease (bacterial)
What are the primary AE’s of penicillin?
nausea, vomiting, diarrhea, rash, black hairy tongue Warnings: hypersensitivity (anaphylactic) reactions, CDAD
What is the brand name for PHENAZOPYRIDINE HCL (Analgesic)?
Pyridium
What is the indication for phenazopyridine?
Infectious disease (bacterial)
What are the CI/warnings for phenazopyridine?
Renal impairment (CrCl < 50 mL/min), severe liver disease
What are the primary AE’s of phenazopyridine?
nausea, headache
What is the brand name for SMX/TMP (Antibiotic/Sulfonamide)?
Bactrim, Septra, Sulfatrim
What is the indication for SMX/TMP?
Infectious disease (bacterial)
What are the CI/warnings for SMX/TMP?
Sulfa allergy, megaloblastic anemia due to folate deficiency, pediatric patients < 2 months
What are the primary AE’s of SMX/TMP?
nausea, anorexia, vomiting, allergic skin reactions Warnings: hepatic necrosis, congenital malformations, hypersensitivity reactions, thrombocytopenia, CDAD, use in folate deficiency, hemolysis in G6PB deficiency, hypoglycemia, hyperkalemia, crystalluria, blood dyscrasias
What is the brand name for ACYCLOVIR (Antiviral)?
Zovirax
What is the indication for acyclovir?
Infectious disease (viral)
What are the primary AE’s of acyclovir?
nausea, vomiting, diarrhea, CNS toxicity Warnings: renal dysfunction, thrombotic thrombocytopenia purpura/hemolytic uremic syndrome
What is the brand name for OSELTAMIVIR (Antiviral)?
Tamiflu
What is the indication for oseltamivir?
Infectious disease (viral)
What are the primary AE’s of oseltamivir?
headache, nausea, abdominal pain Warnings: hypersensitivity (skin) reactions, neuropsychiatric events
What is the brand name for VALACYCLOVIR HCL (Antiviral)?
Valtrex
What is the indication for valacyclovir?
Infectious disease (viral)
What are the primary AE’s of valacyclovir?
nausea, vomiting, diarrhea, CNS symptoms Warnings: renal dysfunction, thrombotic thrombocytopenia purpura/hemolytic uremic syndrome, CNS toxicity
What is the brand name for SUMATRIPTAN SUCCIN (5-HT1 Receptor Agonist)?
Imitrex
What is the indication for sumatriptan?
Migraines
What are the CI/warnings for sumatriptan?
Cerebrovascular disease, uncontrolled HTN, ischemic heart disease, PVD, use of MAOIs, severe hepatic impairment, hemiplegic or basilar migraine
What are the primary AE’s of sumatriptan?
Malaise/Fatigue, Paresthesia, Warm/Cold Sensation, Chest (pain/tightness/pressure and/or heaviness) at higher doses (50mg,100mg), Neck/Throat/Jaw pain, tightness , pressure at higher doses (50mg,100mg)
What is the brand name for APAP/CODEINE (Opioid/Acetaminophen)?
Tylenol w/ codeine
What is the indication for apap/codeine?
Pain
What is the BBW for apap/codeine?
Hepatotoxicity (from acet)
What are the CI/warnings for apap/codeine?
CNS or respiratory depression
What are the primary AE’s of apap/codeine?
CNS depression, constipation, headache, nausea, vomiting, pruritis; physical dependence, psychological dependence, respiratory depression (overdosage)
What is the brand name for CARISOPRODOL (Skeletal Muscle Relaxant)?
Soma
What is the indication for carisoprodol?
Pain
What are the CI/warnings for carisoprodol?
History of porphyria
What are the primary AE’s of carisoprodol?
Dizziness, drowsiness, headache
What is the brand name for DICLOFENAC SOD (NSAID)?
Voltaren
What is the indication for diclofenac?
Pain
What is the BBW for diclofenac?
Cardiovascular events, GI bleeding
What are the CI/warnings for diclofenac?
Asthma, urticaria, or allergic-type reaction to aspirin or other NSAIDs, aspirin triad, perioperative pain during CABG
What are the primary AE’s of diclofenac?
Dizziness, headache, pruritus, abdominal pain/discomfort, anemia, edema, tinnitus, abnormal renal function, increased LFTs
What is the brand name for FENTANYL (Opioid)?
Duragesic (patch), Subsys (SL spray), Actiq (lozenge), Abstral (SL), Lazanda (nasal), Fentora (tablet), Onsolis (film)
What is the indication for fentanyl?
Pain
What is the BBW for fentanyl?
Severe respiratory depression
What are the CI/warnings for fentanyl?
Acute asthma, paralytic ileus, short-term therapy, use in patients who are NOT opioid tolerant
What are the primary AE’s of fentanyl?
Er/LA FDA Opioid REMS (Medication guides required), Constipation, physical dependence, psychological dependence, somnolence, sedation, nausea, vomiting, conversions are tricky…refer to pain notes, increased absorption when heat present (fever, hot bath, tanning beds, etc)
What is the brand name for HYDROCODONE/APAP (Opioid/Acetaminophen)?
Vicodin, Norco, Lortab, Lorcet
What is the indication for hydrocodone?
Pain
What is the BBW for hydrocodone?
Hepatotoxicity (from acet)
What are the CI/warnings for hydrocodone?
CNS or respiratory depression
What are the primary AE’s of hydrocodone?
CNS depression (drowsiness, dizziness, confusion, lightheadedness), Nausea, Constipation, Physical and/or Psychological dependence, hypotension, decreased urination, risk of respiratory depression and hepatotoxicity in overdose
What is the brand name for HYDROMORPHONE HCL (Opioid)?
Dilaudid, Exalgo
What is the indication for hydromorphone?
Pain
What is the BBW for hydromorphone?
Respiratory depression, do not confuse concentrated formulation
What are the CI/warnings for hydromorphone?
Opioid naïve patients, severe asthma, respiratory depression, risk for GI obstruction
What are the primary AE’s of hydromorphone?
CNS depression, constipation, headache, nausea, vomiting, pruritis; physical dependence, psychological dependence, respiratory depression (overdosage); ER form (medication guides required)
What is the brand name for IBUPROFEN (RX) (NSAID)?
IBU, Motrin
What is the indication for ibuprofen?
Pain
What is the BBW for ibuprofen?
Cardiovascular events, GI bleeding
What are the CI/warnings for ibuprofen?
Asthma, urticaria, or allergic-type reaction to aspirin or other NSAIDs, aspirin triad, perioperative pain during CABG
What are the primary AE’s of ibuprofen?
GI effects (Nausea, epigastric pain, constipation, bloating), dizziness, rash, tinnitus, edema
What is the brand name for KETOROLAC TROMETH (NSAID)?
Toradol, Acular (opthalmic), Acuvail (opthalmic), Sprix (nasal spray)
What is the indication for ketorlac?
Pain
What is the BBW for ketorlac?
Cardiovascular events, cerebrovascular events, GI bleeding, hypersensitivity reactions, Do not use before major surgery such as CABG, do not use in advanced renal impairment, or in combo with other NSAIDs; use lower dose in elderly and pts with low body weight, do not use during labor and delivery, limit use to less than 5 days
What are the CI/warnings for ketorlac?
Asthma, urticaria, or allergic-type reaction to aspirin or other NSAIDs, aspirin triad, perioperative pain during CABG, high risk of bleeding, concurrent use with other NSAIDs, PUD
What are the primary AE’s of ketorlac?
Dizziness, drowsiness, headaches, pruritus, rashes, sweating, abdominal pain, nausea, dypepsia
What is the brand name for MORPHINE SULF (Opiod)?
MS Contin, Avinza, Kadian
What is the indication for morpine?
Pain
What is the BBW for morphine?
Fatal respiratory depression, abuse/misuse/diversion potential, do not crush
What are the CI/warnings for morphine?
GI obstruction, severe asthma, paralytic ileus
What are the primary AE’s of morphine?
ER/LA FDA Opioid REMS (Medication guides required), Constipation, physical dependence, psychological dependence, itching, nausea, somnolence, sedation
What is the brand name for NAPROXEN (NSAID)?
Naprosyn
What is the indication for naproxen?
Pain