TOP 300 Flashcards
Acetaminophen 300 mg/Codeine 30 mg DOSE
PO: 1-2 tab q4-6h
Limit: 5 day for acute pain, 3 day for fever
Acetaminophen 300 mg/Codeine 30 mg CIs
BBW: Liver failure (APAP)
Post-op pain in children after tonsillectomy/adenoidectomy
Hepatotox (XS APAP)
Amp/Sulb DOSE
IM,IV: 1.5-3 g q6h
Amp/Sulb CIs
Hepatotox
Anastrozole BRAND
Arimidex
Anastrozole CLASS
Antineoplastic (Aromatase Inhibitor)
Anastrozole DOSE
PO: 1 mg daily
Anastrozole CIs
Decreased bone density
Monitor LDL
Aspirin CIs
Asthma/Rhinitis/Nasal Polyps
No use in children for viral infections (Reyes Syndrome)
Azelastine CLASS
Antihistamine (Histamine H1 Antagonist)
Azelastine DOSE
IN: 1-2 sprays in each nostril 1-2 times per day as
Azelastine CIs
CNS depression
Bimatoprost BRAND
Lumigan; Latisse
Bimatoprost CIs
Pigmentation changes
Bisoprolol BRAND
Zebeta
Bisoprolol CLASS
Beta Blocker (Beta-1 Selective)
Bisoprolol DOSE
PO: 2.5-5 mg daily
Bisoprolol CIs
Cardiogenic shock, HF, 1st degree heart block, sinus bradycardia
Buprenorphine/Naloxone BRAND
Suboxone, Bunavail, Zubsolv
Buprenorphine/Naloxone CLASS
Opioid partial agonist/antagonist
Buprenorphine/Naloxone DOSE
SL: Buprenorphine 2 mg/Naloxone 0.5 mg
OR
Buprenorphine 4 mg/ Naloxone 1 mg
Carisoprodol BRAND
Soma
Carisoprodol CLASS
Skeletal Muscle Relaxant
Carisoprodol DOSE
PO: 250-300 mg TID PLUS HS
Carisoprodol CIs
Potential for drug dependency development
Cefazolin DOSE
IV: 250 mg-2 g q6-12h
Cefazolin CIs
Caution in pts with hx of seizure disorder
Cefepime DOSE
IV: 1-2 g q8-12h
Cefepime CIs
Increased risk of seizure/status epilepticus
Cefoxitin DOSE
IM,IV: 1-2 g q6-8h
Cefoxitin CIs
Peds >3 months; increased risk of eosinophilia and elevated AST
Ceftriaxone DOSE
IM,IV: 1-2 g q12-24h
Ceftriaxone CIs
Hyperbilirubinemia (neonates)
Cefuroxime DOSE
PO: 250-300 mg BID
IV: 750 mg-1.5 g q8h
Clarithromycin DOSE
PO: 250-500 mg BID
OR
1000 mg XR daily
Clarithromycin CIs
CYP3A4 interaction
Hx of QT prolongation/vent. arrhythmia
Clozapine BRAND
Clozaril, FazaClo, Versacloz
Clozapine CLASS
Antipsychotic (Atypical, 2nd generation)
Clozapine DOSE
PO: 12.5 mg daily
Titrated to target dose of 300-450 mg/day.
Max dose = 900 mg/day
Clozapine CIs
BBW: OrthoHypo, syncope, cardiac arrest
BBW: Hepatotox, myocarditis, cardiomyopathy
BBW: Severe neutropenia
BBW: Seizure risk
BBW: Death (elderly pts with dementia-related psychosis)
Conjugated Estrogens DOSE
PO: 0.3-0.625 mg daily (or by cycle)
IM,IV: 25 mg (can repeat q4-6h for up to 24h)
Conjugated Estrogens CIs
BBW: Increased risk of breast cancer
BBW: Endometrial cancer when used in pts with a uterus
BBW: PE/DVT risk increase
Cyclosporine BRAND
Restasis, Cequa
Cyclosporine Class
Immunosuppressant (Calcineurin Inhibitor)
Cyclosporine DOSE
Opth: 1 drop in each eye BID
Cyclosporine CIs
Active ocular infections
Dabigatran CLASS
Anticoag (Direct Thrombin Inhibitor)
Dabigatran DOSE
PO: 150 mg BID
Dabigatran CIs
BBW: Increase risk of thrombosis if prematurely stopped
Darbepoetin CLASS
Hematopoietic Agent (Colony Stimulating Factor)
Darbepoetin DOSE
SC, IV: 6.25-200 mcg per week
Darbepoetin CIs
BBW: Increased risk of CV events
Dexamethasone DOSE
PO, IM, IV: 0.5-9 mg/day DIV q6-12h
Dexamethasone CIs
Systemic fungal infections, immunosuppression
Dexlansoprazole DOSE
PO:
60 mg daily (tx)
30 mg daily (maintenance)
Dexmedetomidine CLASS
Sedative (Alpha-2 Adrenergic Agonist)
Dexmedetomidine DOSE
ICU Sedation
IV: 1 mcg/kg over 10 min; followed by 0.2-0.7 mcg/kg/hr
Surgical Sedation
IV: 1 mcg/kg over 10 minutes (load); followed by 0.6 mcg/kg/hr
Dexmedetomidine CIs
Bradycardia, hypotension, and sinus arrest (with rapid admin)
Diphenoxylate/Atropine BRAND
Lomotil
Diphenoxylate/Atropine CLASS
GI (Antidiarrheal)
Diphenoxylate/Atropine DOSE
PO: 5 mg (diphenoxylate) 4x per day PRN
Diphenoxylate/Atropine CIs
Diarrhea with pseudomembranous enterocolitis
Dutasteride BRAND
Avodart
Dutasteride CLASS
5-alpha Reductase Inhibitor
Dutasteride DOSE
PO: 0.5 mg daily
Dutasteride CIs
Negative impacts on fetal development
Edoxaban BRAND
Savaysa
Edoxaban CLASS
Anticoag (Factor Xa Inhibitor)
Edoxaban DOSE
PO: 60 mg daily
Edoxaban CIs
BBW: Increase in ischemic events if abruptly d/c
Do not use if CrCl>95 ml/min