Top 200 Drugs Flashcards
Brand:Abilify
Generic: Aripiprazole
Class: Atypical Anti-psychotic
MOA: D2/5HT1A agonist & 5HT2A Antagonist
Indication: For Schizophrenia and Bipolar
Brand:Accutane
Generic: Isotretinoin
Class: Anti-acne (Retinoid)
MOA: inhibits sebaceous gland function
Indication: Acne vulgaris
Brand:Adderall(XR)
Generic: Dextro/AmphetamineSalts
Class: CNS Stimulant
MOA: NE/DA Reuptake Inhibitor
Indication: For ADHD
Brand: Advair
Generic: Fluticasone and Salmeterol
Class: Anti-Asthma
MOA: Fluticasone (corticosteroid), Salmeterol (long-acting BB)
Indication:For Asthma and COPD
Brand: Advil/Motrin/Caldolor
Generic: Ibuprofen
Class: NSAID (propionic acid)
MOA: inhibits prostaglandin synthesis (COX)
Indication:For Analgesia
Brand: Aldactone
Generic: Spironolactone
Class: Diuretic (Aldosterone receptor antagonist)
MOA: antagonizes Na/K exhange site in distal tubule
Indication: HBP
Brand: Alphagan (P)
Generic: Brimonidine
Class:Anti-Glaucoma (Alpha-2 Agonist)
MOA: reduces aqueous humor production and increases uveoscleral outflow
Indication:glaucoma
Brand: Altace
Generic: Ramipril
Class: Anti-hypertensive (ACE-I)
MOA: decreases vasopressor activity and aldosterone secretion
Indication:HBP
Brand: Amaryl
Generic: Glimepiride
Class: Hypoglycemic (2nd gen Sulfonylurea)
MOA: stimulates insulin release and sensitivity to peripheral tissues
Indication:Diabetes
Brand: Ambien (CR)/Zolpmist/Edluar
Generic: Zolpidem
Class: Non-barbiturate Hypnotic
MOA: binds BZ1R subunit of GABA-A R
Indication:insomnia
Brand: Amitiza
Generic: Lubiprostone
Class: Laxative
MOA: Cl channel activator increases intestinal fluid secretion
Indication:Irritable bowel syndrome
Brand: Aranesp
Generic: Darbepoetin alfa
Class: Hematopoietic / Erythropoietic
MOA: stimulates progenitor stem cells to produce/differentiation of red blood cells
Indication:anemia
Brand: Argatroban
Generic: Argatroban
Class: Anti-Coagulant
MOA: Direct thrombin active site inhibitor
Indication:Blood Clot
Brand: Aricept
Generic: Donepezil
Class: Cholinesterase Inhibitor
MOA:
Indication:Alzheimer’s Disease
Brand: Arimidex
Generic: Anastrozole
Class: Anti-Neoplastic Agent
MOA: Aromatase inhibition of androstenedione to estrone
Indication:Breast Cancer
Brand: Arixtra
Generic: Fondaparinux
Class: Anti-Coagulant
MOA: binds Anti-thrombin III, neutralizing Factor Xa
Indication:Blood Clot
Brand: Asacol/Apriso/Lialda
Generic: Mesalamine
Class: Anti-Inflammatory, Salicylate
MOA: COX-I, LOX-I, anti-oxidant effects
Indication:Ulcerative Colitis
Brand: Aspirin
Generic: Aspirin
Class: NSAID-Salicylate
MOA: COX-I, Thromboxane A-I
Indication:Analgesia, Anti-coagulant
Brand: Ativan
Generic: Lorazepam
Class: Benzodiazepine (short/med acting)
MOA: Increases GABA affinity
Indication:Anxiety, Anti-convulsant
Brand: Augmentin (XR)
Generic: Amoxicillin and Clavanulanate
Class: Anti-biotic (beta-lactam)
MOA: Amoxicillin (cell wall synthesis), Clavanulanate (beta-lactamase-I)
Indication:Bacterial Infection
Brand: Avelox
Generic: Moxifloxacin
Class: Anti-biotic (Fluoroquinolone)
MOA: Inhibits Topoisomerases II & IV (DNA replication, repair, transcription)
Indication:Bacterial Infection
Brand: Bactrim (DS)/Septra (DS)
Generic: Sulfamethoxazole/ Trimethoprim
Class: Anti-biotic (Sulfonamide)
MOA: Sulfamethoxazole (blocks PABA synthesis of dihydrofolic acid), Trimethoprim (binds dihydrofolate reductase inhibiting production of tetrahydrofolic acid)
Indication:Bacterial Infection
Brand: Bactroban
Generic: Mupirocin
Class: Anti-bacterial
MOA: Inhibits isoleucyl transfer-RNA synthetase (protein synthesis)
Indication:Bacterial Infection (MRSA)
Brand: Boniva
Generic: Ibandronate
Class: Bisphosphonate
MOA: Inhibits osteoclast-mediated bone resorption/turnover
Indication:Osteoporosis
Brand: BuSpar
Generic: Buspiron
Class: Anti-Anxiety (Azaspirodecanedione)
MOA: 5HT1a and D2
Indication:Anxiety
Brand: Byetta
Generic: Exenatide
Class: Anti-diabetic (Glucagon-Like Peptide-1 receptor agonist)
MOA: increases insulin secretion from pancreatic beta cells
Indication:Diabetes
Brand: Bystolic
Generic: Nebivolol
Class: Beta-1-blocker (cardio-selective)
MOA: decreases contractility, HR, renin, sympathetic tone
Indication:HBP
Brand: Cardizem/ Cartia/ Dilacor/ Tiazac
Generic: Diltiazem
Class: Ca channel blocker (Benzothiazepine)
MOA: decreases cardiac contractility and vascular resistance
Indication:HBP
Brand: Cardura (XL)
Generic: Doxazosin
Class: Alpha-1 blocker
MOA: decreases smooth muscle tone in prostate and bladder
Indication:HBP
Brand: Catapres
Generic: Clonidine
Class: Anti-Hypertensive (Alpha-2 agonist)
MOA: reduces vascular resistance, HR, BP
Indication:HBP
Brand: Celebrex
Generic: Celecoxib
Class: NSAID
MOA: COX2 Inhibitor
Indication:Arthritis, Analgesic
Brand: CellCept
Generic: Mycophenolate
Class: Immunosuppressant
MOA: Inosine monophosphate dehydrogenase inhibitor to inhibit purine synthesis
Indication:Organ Rejection
Brand: Chantix
Generic: Varenicline
Class: Nicotinic agonist
MOA: binds alpha-4-beta-2 neuronal nicotinic acetylcholine receptors
Indication:Smoking Cessation
Brand: Cipro (XR)
Generic: Ciprofloxacin
Class: Anti-biotic (Fluoroquinolone)
MOA: DNA gyrase inhibition (DNA synthesis)
Indication:Bacterial Infection
Brand: Claritin (D)
Generic: Loratadine and (pseudoephedrine)
Class: Anti-histamine (Piperidine)
MOA: H1 receptor antagonist
Indication:Allergic Rhinitis
Brand: Cleocin
Generic: Clindamycin
Class: Anti-biotic (Lincosamide)
MOA: 50s ribosomal inhibition
Indication:Bacterial Infection
Brand: Clozaril
Generic: Clozapine
Class: Anti-psychotic (Dibenzodiazepine)
MOA: D1-5 receptor antagonist
Indication:Schizophrenia
Brand: Colchicine
Generic: Cochicine
Class: Anti-gout (Alkaloid)
MOA: inhibits leukocyte chemotaxis, phagocytosis, glycoprotein and the urate production
Indication:Gout
Brand: Combivent/ Duoneb
Generic: Albuterol and Ipratropium
Class: Bronchodilator
MOA: albuterol (BB), Ipratropium (Anti-cholinergic)
Indication: COPD
Brand: Concerta/ Ritalin/ Focalin XR
Generic: Dex, Methylphenidate
Class: CNS Stimulant
MOA: NE and DA reuptake inhibitor
Indication:ADHD
Brand: Cordarone
Generic: Amiodarone
Class: Anti-Arrhythmic class 3 (Benzofuran)
MOA: blocking myocardial K+ and Na+ channel
Indication:Irregular Heart Rate
Brand: Coreg (CR)
Generic: Carvedilol
Class: Alpha/Beta Blocker
MOA: Alpha B (vasodilation in periphery), Beta B (decreases cardiac output)
Indication:HBP
Brand: Cosopt
Generic: Timolol and Dorzolamide
Class: Anti-glaucoma
MOA: Timolol (non-selective beta 1 & 2 B), Dorzolamide (Carbonic Anhydrase Inhibitor- reduces aqueous humor secretion)
Indication:Glaucoma
Brand: Coumadin/ Jantoven
Generic: Warfarin
Class: Anti-coagulant (Coumarin)
MOA: blocks the regeneration of Vit K epoxide, and clotting factors 2, 7, 9 and 10, and proteins C and S
Indication:Blood Clot
Brand: Cozaar
Generic: Losartan
Class: ARB
MOA: inhibits aldosterone-secreting effects
Indication:HBP
Brand: Cubicin
Generic: Daptomycin
Class: Anti-biotic (Lipopeptide)
MOA: disruption of DNA, RNA, and protein synthesis
Indication:Bacterial Infection
Brand: Cymbalta
Generic: Duloxetine
Class: Anti-depressant (SNRI)
MOA: blocks reuptake of NE and 5HT
Indication:Depression, Pain
Brand: Demadex
Generic: Torsemide
Class: Loop Diuretic
MOA: inhibits Na/K/Cl cotransporter (Na and Cl)
Indication:HBP
Brand: Depakote (ER)
Generic: Divalproex (Valproic Acid)
Class: Anti-convulsant, Anti-migraine, Histone Deacetylase Inhibitor
MOA: Increases Gamma-aminobutyric acid (GABA)
Indication:Seizure, Migraine
Brand: Desyrel
Generic: Trazodone
Class: Anti-depressant (Triazolopyridine)
MOA: alpha-1 and 5HT antagonist and SSRI
Indication:Depression
Brand: Detrol (LA)
Generic: Tolterodine
Indication:Urinary Incontinence
Brand: Dificid
Generic: Fidaxomicin
Indication:CDAD (Clostridium dificile associated diarrhea)
Brand: Diflucan
Generic Fluconazole
Indication:Fungal Infection
Brand: Dilantin
Generic: Extended Phenytoin Sodium
Indication:Seizure
Brand: Dilaudid
Generic: Hydromorphone
Indication:Analgesia
Brand: Diovan
Generic: Valsartan
Indication:HBP
Brand: Diprivan/ [Lusedra]
Generic: Propofol/ [Fopropofol]
Indication:General Anesthesia
Brand: Duragesic/ Actiq
Generic: Fentanyl
Indication:Analgesia
Brand: Dyazide/ Maxzide
Generic: Triamterene and Hydrohlorothiazide
Indication:HBP
Brand: Effexor (XR)/ [Pristique]
Generic: Venlaxafine/ [Desvenlaxafine]
Indication:Depression
Brand: Effient
Generic: Pasugrel
Indication:Blood Clot
Brand: Elavil
Generic: Amitriptyline
Indication:Depression
Brand: Elimite/ Nix
Generic: Permethrin
Indication:Head Lice
Brand: Epogen, Procrit
Generic: Epoetin alfa
Indication:anemia
Brand: Evista
Generic: Raloxifene
Indication:Osteoporosis
Brand: Fioricet
Generic: Acetaminophen, Butalbital, and Caffeine
Indication:Analgesia
Brand: Flagyl
Generic: Metronidazole
Indication:Bacterial Infection
Brand: Flexiril
Generic: Cyclobenzaprine
Indication:Muscle Spasms
Brand: Flomax
Generic: Tamsulosin
Indication:BPH
Brand: Flonase/ Flovent
Generic: Fluticasone
Indication:Allergic Rhinitis/ Asthma
Brand: Folic Acid
Generic: Folacin; Pteroylglutamine Acid; Folate
Indication:Anemia
Brand: Foradil/ [Brovana]
Generic: Formoterol/ [Afromoterol]
Indication:Asthma
Brand: Fosamax
Generic: Alendronate
Indication:Osteoporosis
Brand: Gentamicin/ Tobramycin
Generic: Gentamicin/ Tobramycin
Indication:Bacterial Infection
Brand: Glucophage (XR)
Generic: Metformin Hydrochloride
Indication:Diabetes
Brand: Glucotrol
Generic: Glipizide
Indication:Diabetes
Brand: HydroDiuril
Generic: Hydrochlorothiazide
Indication:HBP
Brand: Imdur
Generic: Isosorbide Mononitrate
Indication:Angina
Brand: Imitrex/ Sumavel DosePro/ [Treximet]
Generic: Sumatriptan/ [Sumatriptan and Naproxen]
Indication:Migraine
Brand: Inderal [LA]
Generic: Propanolol
Indication:HBP