Top 100 drugs

Question 1

Name common SSRIs

Answer 1

Sertaline
Citalopram
Fluoxetine
Escitalopram

Question 2

Common indications for SSRI

Answer 2

Mod-to-devere depression
Panic disorder
OCD

Question 3

Adverse effects of SSRI

Answer 3

Weight loss or gain
GI upset
Hyponatraemia
Lower seizure threshold
Prolong QT interval

Question 4

Elderly lady taking SSRI presents with confusion and reduced consciousness

Answer 4

Hyponatraemia ass. with SSRI

Question 5

SSRI + NSAID risk?

Answer 5

• Increased risk of bleeding
• give with omeprazole

Question 6

What drug co prescribed with SSRIs increase risk of Serotonin syndrome

Answer 6

• monoamine oxidase inhibitors
• tramadol

Question 7

What duration once commencing SSRI should the first review be?

Answer 7

1-2 weeks

Question 8

SSRI age <18

Answer 8

fluoxetine

Question 9

How long should SSRI be continued once symptoms improve

Answer 9

Minimum of 6mnths after resolvement of symptoms
up to 2 years for severe depression

Question 10

Diabetic neuropathy what drug prescribed

Answer 10

duloxetine

Question 11

Drug for trimeginal neuralgia

Answer 11

Carbamazepine

Question 12

Migraine prophylaxis

Answer 12

propanolol
Amitriptyline

Question 13

Side effects of TCA

Answer 13

Dry mouth
constipation
urinary retention

Question 14

Name first generation antipsychotics

Answer 14

haloperidol
chlorpromazine

Question 15

Side effects 1st gen antipsychotics

Answer 15

extrapyramidal symptoms (acute dysytonic, akathisia, neuroleptic malignant syndrome)
hyperprolactinaemai

Question 16

name 2nd gen antipsychotics

Answer 16

quetiapine
olanzapine
risperidone
clozapine

Question 17

Antisphycotics and arrhythmias

Answer 17

cause prolongation og QT interval

Question 18

When is clozapine used

Answer 18

Treatment resistant schizophrenia

Question 19

Contraindications to clozapine

Answer 19

Neutropenic patients
severe heart disease

Question 20

Side effect of clozapine

Answer 20

agranulocytosis

Question 21

Dopaminergic drugs side effects

Answer 21

hypotension
nausea
hallucinations
wearing off effect

Question 22

When is memantine commenced before donepezil

Answer 22

In moderate to severe Alzheimer’s

Question 23

Short term side effect of levodopa

Answer 23

abnormal dreams

Question 24

First line for generalised seizure

Answer 24

1st = sodium valoprate

2nd = lamotrigine or levertiacetam

Question 25

Side effects of sodium valporate

Answer 25

• GI upset
• teratogenic
• Thrombocytopenia
• Severe liver injury

Question 26

What monitoring should be done of sodium valproate ?

Answer 26

• liver function before and during first 6mnths

Question 27

Sodium Valporate increases the plasma concentration of which drugs

Answer 27

• lamotrigene
• warfarin

Question 28

Side effects of lamotrigene

Answer 28

blurred vision
dizziness
headache
irritability

Question 29

Antiepiletic of choice in pregnancy

Answer 29

lamotrigene

Question 30

Lamotrigine effect on the COCP

Answer 30

The COCP reduces plasma levels of lamotrigine
Seizure activity may increase when starting the COCP

Question 31

When are triptans contraindicated

Answer 31

• Ischaemic heart disease
• CVD
• PVD
  (due to vasoconstrictor properties)

Question 32

Triptans + SSRI

Answer 32

• Serotonin toxicity
• Triptans + SSRI, TCA, tramadol can cause serotonin syndrome

Question 33

Side effect of topirimate

Answer 33

• weight gain
  (carbonic anhydrase inhibitor)

Question 34

Drug for prophylaxis of migraines

Answer 34

• propanolol
• topirimate
• amitriptyline

Question 35

Side effects of donepezil

Answer 35

• GI upset
• exacerbation of bronchospasm
• EPS