Top 100 Flashcards
Acetaminophen
What are the **3 **brand names for Acetaminophen?
Tylenol®, Tempra®, Atasol®
Acetaminophen
What in the indication for it?
Pain, Fever
Acetaminophen
What is the dosage interval for Acetaminophen?
variable
Acetaminophen
Strength of acetaminophen?
Tab: 160 mg, 325 mg, 500 mg, 650 mg. Chew Tab: 160mg. Supp:
120mg, 160mg 325mg, 650mg Solution: 80 mg/mL, 160 mg/5 mL
Acetaminophen
What is the Common adverse effects of acetaminophen?
GI: constipation, nausea, vomiting. CNS: headache, insomnia.
Acetaminophen
Other information for acetaminophen?
Hepatotoxicity may occur after ingestion of a single dose of more than 7.5 g
(adults) or 150 mg/kg (children); a dose of 10 g or more is potentially fatal in an
adult. Acetylcysteine used in acute overdose. Because of the risk of toxicity,
dosing for children must not exceed 5 doses in 24 hours unless under the
advice of a physician
Indication for Tylenol with Codeine
No. 2, 3®
PAIN
Strengths for Tylenol with Codeine
No. 2, 3®
Tylenol#2 300mg acetaminophen/15mg caffeine/15 mg codeine,
Tylenol#3 300mg acetaminophen/15mg caffeine/30mg codeine
Dosing Interval for Tylenol with Codeine
No. 2, 3®
q4h, or q6h
A/E For Tylenol with Codeine
No. 2, 3®?
Most frequent adverse effects: drowsiness, lightheadedness, dizziness,
sedation, shortness of breath, nausea, vomiting (more prominent in ambulatory
patients). Constipation and abdmonial pain are common.
Allopurinol brand name?
Zyloprim
Allpurinol mechanism of action and indication?
Xanthine oxidase inhibitor; Gout
Allopurinol strenghts?
100 mg, 200 mg, 300 mg
Allopurinol dosage interval?
OD, BID, TID, (any dose > 300 mg needs to be divided)
Allopurinol common adverse effects?
Skin rash (including SJS), usually maculopapular, is the
most commonly reported AE Incidence of skin rash may be increased with renal disorders. GI Also common (diarrhea, intermittent abdominal pain, N/V)
Other points for allopurinol?
Better tolerated when taken with food. Adjust dose in renal dysfunction
ASA
ASA: MoA, Indication?
Salicylate NSAID, antiplatelet agent, pain, fever, inflammation
ASA: Dosage interval?
75, 81, 162, 325, 500, 650, 975, chewable: 80mg, Supp: 150mg/650mg
Brand names for ASA?
Aspirin®, Asaphen®, Entrophen®, Novasen
ECT®, Anacin®
Common AE of ASA?
GI: Nausea, vomiting, diarrhea, dyspepsia, bleeding and/or ulceration. CNS:
tinnitus occurs with large doses
Other Info for ASA
NSAIDs may interfere with antiplatelet effects of aspirin via competitive inhibition. When used for antiplatelet effects, aspirin
should be taken 30-120 minutes before an NSAID. **Do not use in children/teens ** with viral infection (risk of Reye’s syndrome). Contraindicated in last trimester of
pregnancy.
Amlodipine. Whats the brand name and med class?
Norvasc, it is dihydropiridine CCB
Amlodipine Indications? Strengths? Dosage interval ?
HTN, Stable angina. 2.5 mg, 5mg, 10mg. Once daily
Amlodipine A/E
CV: Edema, postural dizziness CNS: Headache GI: has been associated with gingival hyperplasia. Available in combo w Atorvastatin (Caduet). Drug Interactions: CYP 3A4
Apixaban brand name? MoA, Indications?
Eliqiuis, Anticoagulant, Prevention of stroke/systemic embolism in patients with nonvalvular
Afib, and treatment and prevention of VTE
Strengths and dosage interval of Eliquis?
2.5mg, 5mg, taken BID
Common AE of Apixaban?
Bruising, bleeding, nausea
Other info about Apixaban?
Interacts with drugs that inhibit or induce both CYP 3A4 and P-gp. Increased bleeding risk with concomitant use of antiplatelet agents. Dose adjusted based
on age, weight and serum creatinine levels.
Amoxicillin brand name? MoA?
Tevamoxin; antibiotic-semisynthetic penicillin
Amoxicillin indication?
Bacterial infection: Upper respiratory tract. Lower respiratory
tract, UTI, H pylori, Lyme disease
Amoxicillin strengths?
125mg/5 mL, 250 mg/5 mL, 125 mg, 250mg, 500mg
Amoxicillin dosage interval?
q8h, q12h, or single dose for endocarditis prophylaxis before procedure
Common A/E of amoxicillin?
nausea, vomiting, diarrhea , or allergic rash
Amoxicillin other info?
Probenecid inhibits renal tubular excretion ((↑ amoxicillin concentrations))
Amitriptyline brand name, MoA, and indications?
Elavil; Tricyclic antidepressant; Depression, unlabeled uses: pain, migraine progphylaxis enuropathy
Amitriptyline strengths and dosing interval?
10mg, 25mg, 75mg; once daily, usually taken HS
Amitriptyline A/E
Anticholinergic: Dry mouth, Urinary retention, constipation. CNS: drowsiness, fatigue. CV: orthostatic hypotension, tachycardia. Weight gain is common
Other information Amitriptyline
Extremely toxic in overdose: arrhythmia, hypotension, seizures, acidosis. Drug interactions common: CYP 2D6 substrate.
Aripiprazole
antipsychotic. Abilify ®, Abilify Maintenna®
Aripiprazole indications?
- Schizophrenia
- bipolar disorder 1,
- depression (adjunctive
treatment)
Tourette disorder
Aripriprazole AE and other info?
CNS: headache, extrapyramidal reaction, drowsiness, akathisia, fatigue, sedation, agitation, insomnia, anxiety. Endocrine /metabolic: weight gain, increased TG and LDL, reduced HDL increased glucose. GI: nausea, vomiting, constipation. Tremor
Increased mortality in elderly pts with dementia
Atenolol
