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Pharm 329 Top 100 Drugs > Top 100 > Flashcards

Top 100 Flashcards

1
Q

Acetaminophen

What are the **3 **brand names for Acetaminophen?

A

Tylenol®, Tempra®, Atasol®

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2
Q

Acetaminophen

What in the indication for it?

A

Pain, Fever

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3
Q

Acetaminophen

What is the dosage interval for Acetaminophen?

A

variable

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4
Q

Acetaminophen

Strength of acetaminophen?

A

Tab: 160 mg, 325 mg, 500 mg, 650 mg. Chew Tab: 160mg. Supp:
120mg, 160mg 325mg, 650mg Solution: 80 mg/mL, 160 mg/5 mL

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5
Q

Acetaminophen

What is the Common adverse effects of acetaminophen?

A

GI: constipation, nausea, vomiting. CNS: headache, insomnia.

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6
Q

Acetaminophen

Other information for acetaminophen?

A

Hepatotoxicity may occur after ingestion of a single dose of more than 7.5 g
(adults) or 150 mg/kg (children); a dose of 10 g or more is potentially fatal in an
adult. Acetylcysteine used in acute overdose. Because of the risk of toxicity,
dosing for children must not exceed 5 doses in 24 hours unless under the
advice of a physician

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7
Q

Indication for Tylenol with Codeine
No. 2, 3®

A

PAIN

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8
Q

Strengths for Tylenol with Codeine
No. 2, 3®

A

Tylenol#2 300mg acetaminophen/15mg caffeine/15 mg codeine,
Tylenol#3 300mg acetaminophen/15mg caffeine/30mg codeine

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9
Q

Dosing Interval for Tylenol with Codeine
No. 2, 3®

A

q4h, or q6h

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10
Q

A/E For Tylenol with Codeine
No. 2, 3®?

A

Most frequent adverse effects: drowsiness, lightheadedness, dizziness,
sedation, shortness of breath, nausea, vomiting (more prominent in ambulatory
patients). Constipation and abdmonial pain are common.

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11
Q

Allopurinol brand name?

A

Zyloprim

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12
Q

Allpurinol mechanism of action and indication?

A

Xanthine oxidase inhibitor; Gout

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13
Q

Allopurinol strenghts?

A

100 mg, 200 mg, 300 mg

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14
Q

Allopurinol dosage interval?

A

OD, BID, TID, (any dose > 300 mg needs to be divided)

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15
Q

Allopurinol common adverse effects?

A

Skin rash (including SJS), usually maculopapular, is the
most commonly reported AE Incidence of skin rash may be increased with renal disorders. GI Also common (diarrhea, intermittent abdominal pain, N/V)

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16
Q

Other points for allopurinol?

A

Better tolerated when taken with food. Adjust dose in renal dysfunction

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17
Q

ASA

ASA: MoA, Indication?

A

Salicylate NSAID, antiplatelet agent, pain, fever, inflammation

18
Q

ASA: Dosage interval?

A

75, 81, 162, 325, 500, 650, 975, chewable: 80mg, Supp: 150mg/650mg

19
Q

Brand names for ASA?

A

Aspirin®, Asaphen®, Entrophen®, Novasen
ECT®, Anacin®

20
Q

Common AE of ASA?

A

GI: Nausea, vomiting, diarrhea, dyspepsia, bleeding and/or ulceration. CNS:
tinnitus occurs with large doses

21
Q

Other Info for ASA

A

NSAIDs may interfere with antiplatelet effects of aspirin via competitive inhibition. When used for antiplatelet effects, aspirin
should be taken 30-120 minutes before an NSAID. **Do not use in children/teens ** with viral infection (risk of Reye’s syndrome). Contraindicated in last trimester of
pregnancy.

22
Q

Amlodipine. Whats the brand name and med class?

A

Norvasc, it is dihydropiridine CCB

23
Q

Amlodipine Indications? Strengths? Dosage interval ?

A

HTN, Stable angina. 2.5 mg, 5mg, 10mg. Once daily

24
Q

Amlodipine A/E

A

CV: Edema, postural dizziness CNS: Headache GI: has been associated with gingival hyperplasia. Available in combo w Atorvastatin (Caduet). Drug Interactions: CYP 3A4

25
Q

Apixaban brand name? MoA, Indications?

A

Eliqiuis, Anticoagulant, Prevention of stroke/systemic embolism in patients with nonvalvular
Afib, and treatment and prevention of VTE

26
Q

Strengths and dosage interval of Eliquis?

A

2.5mg, 5mg, taken BID

27
Q

Common AE of Apixaban?

A

Bruising, bleeding, nausea

28
Q

Other info about Apixaban?

A

Interacts with drugs that inhibit or induce both CYP 3A4 and P-gp. Increased bleeding risk with concomitant use of antiplatelet agents. Dose adjusted based
on age, weight and serum creatinine levels.

29
Q

Amoxicillin brand name? MoA?

A

Tevamoxin; antibiotic-semisynthetic penicillin

30
Q

Amoxicillin indication?

A

Bacterial infection: Upper respiratory tract. Lower respiratory
tract, UTI, H pylori, Lyme disease

31
Q

Amoxicillin strengths?

A

125mg/5 mL, 250 mg/5 mL, 125 mg, 250mg, 500mg

32
Q

Amoxicillin dosage interval?

A

q8h, q12h, or single dose for endocarditis prophylaxis before procedure

33
Q

Common A/E of amoxicillin?

A

nausea, vomiting, diarrhea , or allergic rash

34
Q

Amoxicillin other info?

A

Probenecid inhibits renal tubular excretion ((↑ amoxicillin concentrations))

35
Q

Amitriptyline brand name, MoA, and indications?

A

Elavil; Tricyclic antidepressant; Depression, unlabeled uses: pain, migraine progphylaxis enuropathy

36
Q

Amitriptyline strengths and dosing interval?

A

10mg, 25mg, 75mg; once daily, usually taken HS

37
Q

Amitriptyline A/E

A

Anticholinergic: Dry mouth, Urinary retention, constipation. CNS: drowsiness, fatigue. CV: orthostatic hypotension, tachycardia. Weight gain is common

38
Q

Other information Amitriptyline

A

Extremely toxic in overdose: arrhythmia, hypotension, seizures, acidosis. Drug interactions common: CYP 2D6 substrate.

39
Q

Aripiprazole

A

antipsychotic. Abilify ®, Abilify Maintenna®

40
Q

Aripiprazole indications?

A
  • Schizophrenia
  • bipolar disorder 1,
  • depression (adjunctive
    treatment)
    Tourette disorder
41
Q

Aripriprazole AE and other info?

A

CNS: headache, extrapyramidal reaction, drowsiness, akathisia, fatigue, sedation, agitation, insomnia, anxiety. Endocrine /metabolic: weight gain, increased TG and LDL, reduced HDL increased glucose. GI: nausea, vomiting, constipation. Tremor
Increased mortality in elderly pts with dementia

42
Q

Atenolol

A

Pharm 329 Top 100 Drugs (1 decks)

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