Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Growth and Development part 2 > Tooth Development > Flashcards

Tooth Development Flashcards

1
Q

First sign of tooth development is at _____ weeks in utero

A

6-7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Deciduous teeth begin to calcify at _______ weeks in utero

A

13-20

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Deciduous teeth erupt at _____ months

A

6-30

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

By _____ weeks in utero all deciduous teeth have begun to calcify

A

18-20

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

First part of tooth to calcify is the ____

A

crown

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the basic steps of tooth development?

A
  • initiation
  • morphogenesis
  • cell differentiation
  • matrix secretion
  • eruption
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the stages of tooth development?

A

I. Crown Formation:
1. Initiation
2. Bud Stage
3. Cap Stage
4. Bell Stage
5. Enamel and dentin formation
II. Root Formation
III. Supporting Structures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the stages of crown formation?

A
  1. Initiation
  2. Bud Stage
  3. Cap Stage
  4. Bell Stage
  5. Enamel and dentin formation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the name of the epithelium that begins the oral cavity in the developing human head?

A

odontogenic epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What does the primary epithelial band give rise to?

A
  • dental lamina
  • vestibular lamina
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the characteristics of the primary epithelial band?

A
  • Horseshoe shaped
  • Correspond to future dental arches
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

_____ Is Expressed In The Epithelium And _____ In The Mesenchyme

A

Shh
Pax9

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What happens during initiation of tooth development?

A
  • Placode formation/Epithelial thickening.
  • Epithelial outgrowth into the mesenchyme
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

The neural crest mesenchyme induces the oral ectoderm to become the…

A

dental lamina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Initial odontogenic potential lies in the epithelium subsequently shifts to _________

A

mesenchyme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Does the epithelium change during the bud stage?

A

NO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What genes are involved in placode formation during bud stage?

A

Shh, Lef-1 and Eda-Edar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What happens during the bud stage?

A
  • Shh, Lef-1 and Eda-Edar involved in placode formation
  • Mesenchyme beneath starts to condense by the factors secreted by the epithelium
  • Cross-talk between the epithelium and the mesenchyme
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What two basic processes occur during bud stage?

A
  • morphogenesis (tooth size and shape)
  • progress (developmental arrest)
19
Q

What happens during the cap stage?

A
  • Epithelium proliferates.
  • Mesenchyme continue to condense.
20
Q

What makes up the tooth germ?

A
  • Enamel organ – Enamel of the tooth
  • Dental papilla – Dentin (outer) and pulp (inner)
21
Q

Bud to cap stage transition is regulated by…

A

signaling molecules and transcription factors

22
Q

What does the dental follicle/dental sac form?

A

Supporting structures
- (Cementum / Periodontium / alveolar bone proper)

23
Q

What is the enamel knot?

A

It is a key signaling center consist of cluster of non-dividing cells determines cusp formation.

  • Primary and secondary enamel knot
24
Q

What happens during cap stage histodifferentiation?

A
  • Cells in the enamel organ synthesize glycosaminoglycans into the ECM. Hydrophilic and pull water in to enamel organ
  • Increase in fluid volume force the cells apart leading to formation of star shaped stellate reticulum cells
25
Q

What are the two types of enamel organ epithelial cells?

A
  • Inner enamel epithelium
  • Outer enamel epithelium
26
Q

What happens during early bell stage?

A

1.Under surface of the epithelium deepens and resemble a bell
2.Stratum intermedium formation
3.Crown attains full size and shape

27
Q

What happens during the morphodifferentiation of the bell stage?

A
  • Low Cuboidal shaped outer enamel epithelium (OEE)
  • Short columnar shaped inner enamel epithelium (IEE – will differentiate into ameloblasts)
28
Q

The junction of IEE and OEE is called
_________ – also the future site of the _____

A

cervical loop (CL)

CEJ

29
Q

What happens during late bell stage?

A
  • Dental lamina breaks and the separates the tooth from oral epithelium
  • Inner enamel epithelium (IEE) completes folding forming the future crown pattern
  • Under the influence of IEE mesenchymal cells differentiate into odontoblasts that makes dentin
  • Subsequently IEE differentiate in to ameloblasts and make enamel
30
Q

Site at which IEE differentiates determines future ______ formation

A

cusp

31
Q

IEE differentiate in to _____________ and makes _________

A

ameloblasts
enamel

32
Q

Under the influence of IEE mesenchymal cells differentiate into __________ that makes ______

A

odontoblasts
dentin

33
Q

What is the folding due to in order to form the crown pattern?

A

differential rates of mitotic division in IEE

34
Q

Ameloblasts are derived from what type of cells?

A

inner enamel epithelium

35
Q

What are the stages of amelogenesis?

A
  1. Morphogenetic stage
  2. Histodifferentiation stage
  3. Initial secretory stage (no Tome’s process)
  4. Secretory stage (Tome’s process)
  5. Ruffle ended ameloblast of the maturation stage
  6. Smooth ended ameloblast of the maturation stage
  7. Protective stage
36
Q

What happens during the secretory stage of ameloblasts?

A
  • Intense synthetic and secretory activity
  • Forms enamel rod (R) and inter-rod (IR)
  • Secrete granules on the newly formed mantle dentin.
37
Q

What are the proteins and proteases secreted during secretory stage by ameloblasts?

A

Proteins:
- Amelogenin
- Ameloblastin
- Enamelin
Proteases
- Enamelysin (MMP20)
- Kallikrein

38
Q

Under the influence of epithelial cells mesenchymal cells differentiate into odontoblasts that make…

A

dentin

39
Q

What is mantle dentin?

A

First layer of dentin formed by the newly differentiated odontoblasts, hypomineralized, and only in the crown of the tooth (30-50um thick)

40
Q

What is primary dentin?

A

Formed during tooth development (4um/day)

41
Q

What is secondary dentin?

A

Dentin formed after tooth eruption (0.4um/day)

42
Q

What is teriary dentin?

A

Dentin produced in response to injury to protect the pulp

43
Q

IEE and OEE form the cervical loop proliferate downward to form double layered structure called…

A

Hertwig’s epithelial root sheath

43
Q

Fragmentation of Hertwigs epithelial root sheath (HERS), mostly removed before ________ is laid down

A

cementum

44
Q

Remnants of HERS are called…

A

epithelial rests of Malassez

Growth and Development part 2 (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions