toksikologi, interaktioner og udvikling Flashcards

1
Q

lægemiddel der er extra følsomt overfor interaktioner m andre lægemidler

A

warfarin

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2
Q

vigtigste farmakodynamiske interaktion

A

sildenafil og nitroglycerin

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3
Q

Cytokrom P450 inducerende stoffer

A

carbamazepin , rifampicin –> CYP3A4

ethanol

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4
Q

Cytokrom P450 hæmmende stoffer (CYP3A4)

A

ritonavir, erythromycin, grapefrugt

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5
Q

Prodrugs : lægemidler med aktive metabolitter

A

clopidogrel, codein, tamoxifen, losartan, valaciclovir

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6
Q

teratogene stoffer

A

thalidomid

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