Tobacco Flashcards

1
Q

What is the single biggest cause of preventable morbidity and mortality in the NHS?

A

Tobacco related disease.

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2
Q

What diseases are associated with smoking?

A
Cardiovascular disease: MI and stroke,
Lung cancer.
Infantile sudden death.
Influenza.
Basically everything.
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3
Q

What is cigarette smoking?

A

A chronic relapsing disorder that starts in adolescence. The nicotine causes the addiction not the harm of the tobacco.

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4
Q

What are the markers for addiction?

A
  1. Use despite knowledge of harmful consequences.
  2. Craving during abstinence.
  3. Failure of attempts to stop.
  4. Withdrawal symptoms during abstinence.
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5
Q

What is the physiology of nicotine?

A

Nicotine acts on nicotinic acetylcholine receptor stimulating dopamine release.
Creates satisfaction.
Following chronic nicotine exposure, ACh enters the unregulated state which increases the affinity and functional sensitivity to an agonist.

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6
Q

How long does it take for ACh receptors to desensitise after the last cigarette?

A

6-12 weeks.

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7
Q

How can you help patients to stop smoking?

A
  1. Ask: smoker/non-smoker.
  2. Advice.
  3. Act.
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8
Q

How can you treat a smoking addiction?

A
  1. Champix: ACh agonist to decrease desire to smoke.
  2. Nicorette gum.
  3. Spray.
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9
Q

What is a harm reduction strategy for smoking?

A

E-cigarettes. Decrease smoking with continuous nicotine use.

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10
Q

What re the different types of nicotine devices?

A
  1. First Generation: looks like a cigarette.
  2. Second Generation: pen like.
  3. Third Generation: power steering.
  4. Fourth Generation: heat not burn.
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11
Q

What are the advantages of using an e-cigarette?

A
  1. Nicotine is a minor health risk.
  2. Negligible compared to tobacco.
  3. Allows patients to ease off smoking and eventually quit.
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12
Q

What are the disadvantages of using an e-cigarette?

A
  1. Continues to use nicotine.
  2. Long term effects unknown.
  3. Dual use perpetuates smoking.
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