Tissue Respone To Injury Flashcards
Passive structure
Tendons= attach muscles to bones and transmission of tensile load
Ligaments and joints capsule = preventions of excessive motion, enhance mechanical stability, guide the joint motion
What does unhealthy tissue consist of and which one is the most common type
Unhealthy tissue consists of T3
T1. Is most common one
Elasticity
Related to the ability that material to return its original dimensions after loading
Stress strain curve
It’s has three regions
Elastic region: its deforms elastically, meaning that it can return its original shape when the stress is removed. The stress and strain is linear in this region
Yield point: the point at which the material transition from elastic deformation to plastic deformation beyond this point, the material will not return to it’s original shape when the stress is removed
Plastic region: the material goes under goes permanent deformation as there stress continues increases and the relationship btw stress and stain is no longer linear
Ultimate tensile strength: ust is maximum stress that a mcan withdraw before its failure occurs
Fracture points; its fails and either by fracture or rupture
Inflammation
Define as local response of living tissue to injury due to any agent
And body defense reactions to eliminate or limit the spread of the injurious agent to bring the immune system
Symptoms and sight of inflammation
Redness swelling heat pain
Three phases of soft tissue healing
Inflammatory- response phase
Proliferation- repair phase
Mutations- remodeling phase
Inflammatory phase
This phase begins immediately after an injury and can last up to 6 days. During this phase, the body’s immune system responds to the injury by sending white blood cells, nutrients, and oxygen to the area. This results in redness, swelling, tenderness, and increased temperature. This phase is critical for the entire healing process.
Proliferation
This phase can last up to 3 weeks and involves the formation of new tissue. Fibroblasts, which are specialized cells that produce collagen, migrate to the injured area and begin forming new tissue. Blood vessels also begin to form in the area, which helps to supply oxygen and nutrients to the new tissue.
Remodeling
This phase can last up to a year and involves the remodeling of the new tissue. The tissue becomes stronger and more organized as collagen fibers align in the direction of stress. This phase is important to ensure that the new tissue can withstand the normal stresses placed upon it.
Healing process of ligaments
Tough, relatively inelastic band of tissue that connects
bone to bone
During next 6 weeks-vascular proliferation with new
capillary growth and fibroblastic activity
◦ Full healing may require 12 months
Healing process for cartilage
Limited capacity to heal
• Little or no direct blood supply
• Chondrocyte and matrix disruption result in
variable healing
If area involves subchondral bone (enhanced
blood supply) granulation tissue is present and
healing proceeds normally
Component of soft tissue
Epithelial tissue
Muscular tissue
Neural tissue
Connective tissue
Factors causing dysfunction in soft tissue
*Scar formation: scar formation after surgery, scar formation after inflammation of the capsule
*Limitation of lymphatic circulation and swelling:
*Ground substances dehydration and intermolecular cross link
Fascia
Is specialized connective tissue that surrounds every nerve muscle bone blood vessels