Tissue Plasminogen Activator (TPA) Flashcards
1
Q
what is an example of a TPA
A
Alteplase
2
Q
What does a TPA do
A
activates Plasminogen ==> Breaks down plasmin ==> Breaks down clots
3
Q
What 3 conditions can a TPA be used in
A
PE
Acute MI
Acute ischaemic stroke
4
Q
what are 3 contraindications of a TPA
A
Acute pancreatitis
recent Sx
Coagulation defects
5
Q
what class of drugs should a TPA not be given with
A
anti-coagulants (excessive bleeding)
==> heparin // Enoxaparin
6
Q
What are 3 sideeffecstof taking a TPA
A
hypotension
Haemorrhage
Angina pectoris
