Tissue healing Flashcards
Skeletal muscle structure
- Collegen
- Elastin
- Connective tissue
Muscular structure properties
- Extensibility: Capacity to stretch to the normal resting length after contracting
- Excitability: Ability to respond or contract in response to chemical/electrical signals
- Elasticity: Ability to return to original resting length after a muscle has been stretched
- Contractibility: Ability to shorten causing movement of structures to which muscles are attached
Strain Curve
Elastic region: Will return to original shape with given stress
Plastic region: Will not return to original shape with given stress
Tissue deformity
Yield point: Plastic behaviours
Plastic region: Microscopic failure
Soft tissue healing
May include - cellular pathology, cell necrosis, wound healing, inflammation
Phases of tissue healing
- Bleeding
- Inflammation
- Repair
- Re modelling
Bleeding phase
Stopping blood when an injury occurs
- Vasoconstriction: blood vessels narrow to ^ blood pressure
- Plug formation: Adherence of platelets into a plug
- Coagulation: Fibrin mesh is made from fibrinogen (acts as a glue)
A scab is formed
Inflammation 1-5 days
Body’s attempt to heal itself from tissue damage
Acute - Initial response to harmful stimuli
Chronic - Follows acute
Proliferation (repair) 3-21 days
-Fibroblasts migrate to the area from surrounding tissue within the first few days due to chemical mediation
- Capillaries re-establish blood flow
- O2 helps with collegen production (helps with scaring)
Remodelling 14 days - 2 years
- Type 3 collegen is reabsorbed
- Type 1 is now more abundant
- Optimal loading is required for strength of collegen
- Scar tissue formation