Tissue And Organ Response To Radiation And Gentic Effects Of Radiation

Question 1

For diagnosis which ray is used

Answer 1

Gamma ray

Question 2

For treatment which ray is used

Answer 2

Beta-ray

Question 3

2 actions of ionizing radiation on cells

Answer 3

Direct
Indirect

Question 4

Direct action

Answer 4

Interaction of radiation with a critical molecule necessary for the survival of the cell
DNA,enzyme

Question 5

Indirect action

Answer 5

Radiation effects occur through some nonessential molecules
Usually water
Free radicals as an end product
More prominent then direct action

Question 6

Free radicals causes

Answer 6

Biological damage

Question 7

Which cells are the most radiosensitive

Answer 7

Precursor cells of hematopoietic system
GI tract
Gonads
Lymphocytes
Erythroblast
Intestinal epi
Germ cells

Question 8

Relation of differentiation of cells and radiosensitivity

Answer 8

Degree of differentiation of cells is inversely related to the radiosensitivity

Question 9

In which phases cell is more radiosensitive

Answer 9

M
G2

Question 10

In which phases cell is more resistant to radiation

Answer 10

G1
S

Question 11

Less radiosensitive cells

Answer 11

Dermal epi
Endothelium
Salivary glands
Growing bone and cartilage

Question 12

Least radiosensitive cells

Answer 12

Kidney cells
Liver
Mature bone and cartilage
Muscle and nervous system

Question 13

Which organs are the most sensitive organs to radiation induced cancer

Answer 13

Active bone marrow
Breast
Thyroid
Lungs

Question 14

Risks of inutero exposure

Answer 14

In the preimplantation stage radiation exposure ALL OR NONE effect
Organogenesis is the most critical period for radiation induced congenital malformations
Fetus is more radio resistant beyon the organogenesis

Question 15

2 types of Dose-Effect curves for radiation exposure

Answer 15

Nonstochastic effect
Stochastic effect