'Tis the season (Influenza) Flashcards

1
Q

What is meant by “trivalent vaccine?”

A

The trivalent vaccine protects against 2 influenza A viruses and an influenza B virus

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2
Q

Is the trivalent vaccine grown in eggs?

A

Yes. Therefore: don’t give to pts with an egg allergy

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3
Q

What is a “quadrivalent vaccine?”

A

The quadrivalent vaccine protects against 2 influenza A viruses and 2 influenza B viruses

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4
Q

Does the CDC recommend the trivalent or the quadrivalent vaccine? Additionally, what does the CDC recommend between injection vs inhaled vaccine?

A

No. CDC does not recommend one vaccine over another. The important thing is to get a flu vaccine every year. This includes inhaled vs injected…

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5
Q

Once you’ve had the vaccine, how long does it take for the body to develop antibodies and protect against influenza virus?

A

About 2 weeks

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6
Q

At what age does the CDC recommend children begin receiving the flu vaccine?

A

6 months

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7
Q

An elderly patient is taking Tamiflu for prophylactic treatment of influenza. Would the influenza vaccine be appropriate for him/her?

A

Yes. Administration of inactivated influenza vaccine to persons receiving influenza antiviral drugs for treatment or chemoprophylaxis is acceptable (CDC)

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8
Q

A family comes in to receive the flu vaccine. The youngest child is 5 y.o., and is also receiving his MMR. Can this child receive the influenza vaccine?

A

Yes. Inactivated vaccines do not interfere with the immune response to other inactivated vaccines or live vaccines.

Inactivated or live vaccines can be administered simultaneously with live-attenuated influenza vaccine

However, after administration of a live vaccine, at least 4 weeks should pass before another live vaccine is administered

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9
Q

Oseltamavir and zanamivir are __________ inhibitors

A

neuraminidase

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10
Q

Neuraminidase inhibitors have activity against which viruses?

A

Influenza A and B

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11
Q

A CNA has tested positive for influenza virus B. The decision is made to begin chemoprophylaxis to prevent the disease in the patients she cares for. One patient has COPD. Which antiviral is recommended?

A

Oseltamivir (Tamiflu). Zanamivir (Relenza) is not recommended for use in people with underlying respiratory disease (e.g., asthma, COPD)

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12
Q

H1N1 influenza is especially dangerous to whom?

A

Obese and pregnant people

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13
Q

What is ‘the stomach flu’?

A

There is no such thing!

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14
Q

What type (family) of virus does influenza belong to?

A

Orthomyxoviridae

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15
Q

What capsule protein does the influenza virus use for adsorption to sialic acid - receptors which are found on RBCs and on receptors in the upper respiratory tract?

A

Hemagglutinin (HA)

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16
Q

What is neuraminic acid?

A

An important component of mucin, the substance covering mucosal epithelial cells and forming an integral part of the host’s upper respiratory defense barrier.

17
Q

What is the function of the influenza protein neuraminidase (NA)?

A

Disrupts the mucin barrier, exposing the sialic acid binding sites beneath. NA is also critical for the newly formed virion from the infected host cell. The NA allows the virus to escape the infected cell in order to go out and infect another

18
Q

Is influenza an ‘airborne’ or a ‘droplet’ infectious agent?

A

droplet. Only 3 airborne infectious agents which require airborne precautions:(recognized by CDC): TB, Measles, Chickenpox