Tinea versicolor Flashcards
Etio
Malassezia furfur and M.globosa
manifestation
Chronic.Well-demarcated patches with fine scale. Variable pigmentation:Hypo- and hyperpigmented; pink. Most commonly on the trunk.
Demography
Young adults
Predisposing factors
Sweating.Warm season or climates;tropical climate.Hyperhidrosis;aerobic exercise.Oily skin.Temperate zones:More common in the summertime;2%prevalence in temperate climates;up to 50% in tropics.Application of lipids such as cocoa butter
Pathogenesis
Malassezia changes from a yeast to hyphal form under the influence of predisposing factors. Produces dicarboxylic acid, which inhibits tyrosinase in epidermal melanocytes and leads to
hypomelanosis
Color
In non tanned skin lesions are brown or pink. On tanned skin, hypopigmented. In brown- or black-skinned persons, dark brown macules. Brown of varying intensities and hues. In time, individual lesions may enlarge and merge, orming extensive geographic areas.
Distribution
Upper trunk, upper arms, neck, abdomen, axillae, groins, thighs, genitalia
Diagnostics
KOH- Filamentous hyphae and globus yeast forms
Woods lamp- Blue green fluoresence of scales
Treatment
topical agents.Selenium sulfide(2.5%)lotion or shampoo. Ketoconazole shampoo. Azole creams (ketoconazole, econazole, micronazole, or clotrimazole). terbinafine 1% solution
Systemic therapy Fluconazole 300 mg weekly × 3 weeks. Itraconazole 400 mg (singledose).
Secondary prophylaxis. topical agents weekly or systemic agents monthly