Tigecycline Flashcards
1
Q
How does tigecycline compare to tetracyclines?
A
Similar side effects and similar MOA
2
Q
What are tigecyclines used for?
A
Tetracycline sensitive G+/G- microbes and MRSA
Parenteral for complicated skin infections, intra-abdominal infections, CABP
3
Q
What do you do to the does or tigecycline if there is severe hepatic impairment?
A
Decrease dose
4
Q
What is the FDA warning for tigecycline?
A
Increased risk of death, particularly if hospital acquired, ventilator assisted pneumonia