Tick Diseases Flashcards
What organism causes Lyme Disease
Borrelia burgdorferi (spirochete)
organism that causes babesiosis
Babesia microti
organism that causes Granulocytic anaplasmosis
anaplasma phagocytophilum
organism that causes monocytic ehrlichiosis
ehrlichia chaffeensis
organism that causes RMSF
Rickettsia rickettsi
Lyme Disease:
Regional distribution?
Least common tick borne infection in the US?
western black-legged tick -west coast, deer tick, east-south-east
no, the most common!
Ixodes scapularis nymphs are responsible for most human cases (vector)
reservoir?
duration of tick attachment….
borrelia burgdorferi transmission of lyme disease
reservoir = small rodents
> 24 hr, enough time to transfer VFs to the blood
systemic sxs with local evidence of infection at tick bite (erythema chronicum migrans and constitutional sxs)
primary LD (days to weeks)
clinical Dx - no tests needed
most don’t recall tick bite
secondary LD (dissemination)
Clinical Dx
manifestations of disease remote from tick bite, >3-4 weeks
-malaise, MS sxs, dermatologic (EM), cardiac (AV-c abnl) and neurologic signs (bell’s palsy)
late manifestations, remote from site, >6 months, oligoarticular arthritis of lg joints, peripheral neuropathy (rare)
tertiary LD (persistent infection)
methods for LD Diagnosis
better if secondary or tertiary disease
- ELISA, Immunoblot (>5/10 for IgG or >2/3 for IgM)
- people can seroconvert (false +)
LD serology
for tertiary cases, atypical presentations
LD treatment
PO (Doxy!) - 1 or 2, some complications
IV (ceftriaxone)- meningitis, hospitalized, recurrent arthritis
for 2-4 weeks
Babesiosis:
vector?
protozoal parasite of RBCs, IP of 1-4 weeks
- Ixodes scapularis (same geo as LD)
- can be spread by transfusion and can be concurrent with LD
Weeks of persistent parasitemia results in…
nothing, most ppl with babesiosis are asymptomatic
-if they have sxs: nonspecific, but signif in splenctomized pt
