Tic Tac Toe Method- determining acid base imbalance Flashcards

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1
Q

Step #1 Determine nml range:
pH 7.35-7.45 (> 7.45 means alkaline)
PCO2 35-45* ACIDIC (>45 means acidic)
HCO3 22-26

Step #2 Make grid;    
          Acid/NML/Base
PH
PCO2
HCO3

Step #3 Put X in grid for pt results for each value:

A
Ex: Patient Results: 
ph 7.47: base; PCO2 31: base; HCO3 24: nml
             Acid/NML/Base
PH                             X
PCO2                        X
HCO3             X
Pt has Respiratory Alkalosis!
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2
Q
Acid/NML/Base
PH
PCO2
HCO3
* Pt values: pH 7.46; PO2 86; HCO3 24
A
Acid/NML/Base
PH
PCO2
HCO3
Pt has:
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3
Q
Acid/NML/Base
PH
PCO2
HCO3
Patient values: pH 7.57; PO2 88; PCO2 36; HCO3 30
A
Acid/NML/Base
PH
PCO2
HCO3
Patient has:
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4
Q
Acid/NML/Base
PH
PCO2
HCO3
Patient values: pH 7.3; PO2 72; PCO2 50; HCO3 26
A

Patient has:

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5
Q
Acid/NML/Base
PH
PCO2
HCO3
Patient values: pH 7.14; PO2 70; PCO2 35; HCO3 19
A

Patient has:

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6
Q

Sources of Acid/Base in the Body:

Acids:

A
H+ ions
Ketoacids
carbon dioxide
lactic acid 
Results: low K (hypokalemia)
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7
Q

Sources of Acid/Base in the Body:

Base:

A

Bicarbonate

Results: increased pH

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8
Q

Sources of Acid/Base in the Body:

Compensatory mechanism:

A

*chemical buffers on the scene- in seconds
*respiratory- retention OR elimination of CO2- in minutes
*renal- regulates bicarbs (HCO3) to combat hydrogen losses & gains- in hours, but > permanent when other 2 mechanisms fail.
(Renal system slowly gets to work & requires up to 5 days to complete healing.)

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9
Q

General ACIDOSIS sxs: “low, slow, & weak”

A
Neuro: confusion- 1st sxs
             decreased DTRs
              muscle weakness
CV:        weak pulses
              bradycardia
              hypotension
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10
Q

General ACIDOSIS sxs: “low, slow, & weak”

Causes:

A
Hypoventilation
Drug overdose
Pulmonary Edema
Mechanical ventilation
Mechanical NM Dz
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11
Q

Respiratory Acidosis

A

ph LOW

CO2 HIGH

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12
Q

Metabolic Acidosis

A

ph LOW

HCO3 LOW

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13
Q

Metabolic Acidosis

Causes:

A
DKA
ASA (salicylic acid) overdose
Renal failure
severe diarrhea 
shock
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14
Q

Respiratory Acidosis

TXMT:

A

Meds:
(ex: naloxone, bronchodilators, mucolytics- thin secretions)

O2 (w/ caution! Use lowest art possible)
Mechanical ventilation
Tx the Cause

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15
Q

Metabolic Acidosis

Txmt:

A

Tx the cause (i.e., stop diarrhea, provide O2/insulin drip)

Give sodium bicarbs if pH < 7.2

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16
Q

Hyperventilation

Results in:

A

Respiratory Alkalosis

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17
Q

Respiratory Alkalosis

A

pH high

CO2 low

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18
Q

Respiratory Alkalosis

Causes:

A
initial stages of Pulmonary Emboli
hypoxia
fever 
pregnancy
high altitudes
anxiety
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19
Q

Metabolic Alkalosis:

A

pH high

HCO3 high

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20
Q

Metabolic Alkalosis:

Causes:

A

Overuse of antacids
K+ wasting diuretics
(Increased loss of H+)
Loss of gastric juices

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21
Q

General Alkalosis SXS “Excitable & Weak”

A
Dizziness
Confusion
Hyperreflexia
Numbness/tingling (mouth/toes)
Cramps/Twitching
Tachycardia
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22
Q

Alkalosis

TXMT:

A

Tx the cause
Fall precautions
Rebreather mask (respiratory alkalosis)

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23
Q

ABG Interpretation Rules to Remember:

A
CO2= Respiratory & ACID
HCO3= Metabolic (kidney) & base/alkaline
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24
Q

ABG Interpretation Rules to Remember:
Steps:
-Acid or Base? look at the pH
Respiratory or Metabolic? use ROME method

A

ROME:
Respiratory pH high; PCO2 low
Opposite pH low; PCO2 high
Metabolic pH high; HCO3-high (alkalosis)
Equal pH low; HCO3-low (acidosis)

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25
Q

Na+ Imbalance Electrolyte

Fx/indication of imbalance

A
  • Na+ serves as primary determinant of blood osmolarity.

* It’s an important regulating acid/base balance & contributes to Fx of nervous system & other excitable tissue.

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26
Q

Na+ Imbalance Electrolyte

SXS of Hyponatremia:

A
Muscle cramps
weakness
HA 
depression
apprehension
feeling impending doom
personality changes
lethargy
stupor
coma
anorexia
N/V
abd cramps
diarrhea
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27
Q

Na+ Imbalance Electrolyte

SXS of HYPERnatremia:

A
  • Polydipsia
  • oliguria/anuria/high urine specific gravity
  • dry skin/mucous membranes; decreased tissue turgor
  • tongue- rough/fissured
  • decreased salivation/tears
  • agitation/restlessness
  • HA/SZ/coma/decreased reflexes
  • tachycardia; weak, thready pulse; low BP/vascular collapse
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28
Q

Cl- (chloride)
Fx/indications of imbalance
(extracellular)

A

Most often assoc w/ Na+

Plays role in reg of acid/base balance

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29
Q

Cl- (chloride)
LOW LEVELS: hypochloremia
SXS:

A
increased muscle tone
twitching 
weakness
tetany
shallow breathing
respiratory arrest
mental confusion
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30
Q

Cl- (chloride)
HIGH LEVELS:
HYPERchloremia
SXS:

A
metabolic acidosis
deep, rapid breathing
weakness
HA
diminished cognitive ability
cardiac arrest
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31
Q

Imbalance of K+
K+ is intracellular cation
Fx/indication of imbalance:

A

Distribution of K+ b/w intracellular & extracellular compartments regulates electrical membrane potentials, controlling excitability of nerve & muscle cells & contractility of skeletal, cardiac, & smooth muscle tissue.

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32
Q

Hypokalemia

sxs:

A
dizziness
muscle weakness/leg cramps
cardiac arrhythmias/hypotension
nausea/anorexia/thirst 
poorly concentrated urine/polyuria
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33
Q

HYPERkalemia

sxs:

A
N/V/D/abd/intestinal cramps
cardiac arrhythmias
paresthesias/weakness
muscle cramps
EKG changes; R/F: cardiac arrest (w/ very elevated K+)
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34
Q

Mg++
(intracellular)
Fx/indication of imbalance:

A

Acts as a cofactor in many IC enzyme reactions; is essential to all reactions requiring ATP, for every step r/t replication & transcription of DNA; & for translation of mRNA & required for cellular energy metabolism.

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35
Q

Hypomagnesemia

sxs:

A

Usually occurs w/ hypocalcemia & hypokalemia

sxs: personality changes, athetoid or choreiform movts, nystagumus, tetany…tachcardia, HTN, & cardiac arrhythmias.

36
Q

HYPERmagnesemia

sxs:

A

lethargy
hyporeflexia
confusion/coma
hypotension/cardiac arrhythmias/cardiac arrest

37
Q
HCO3 bicarbonate (extracellular)
fx/indication of imbalance:
A

One way the body maintains nml pH is via chemical buffers in the ICF & ECF. The most important is HCO3 buffer system.

  • A reduction in pH d/t increased HCO3: metabolic acidosis
  • An elevation in pH d/t increased HCO3 levels: metabolic alkalosis
38
Q

Metabolic Acidosis

sxs:

A
anorexia/N/V/abd pain
weakness/lethargy/general malaise
confusion/stupor/coma
depression of vital fx: 
peripheral vasodilation, decreased HR, cardiac arrhythmias
skin- warm/flushed
bone dz (e.g. chronic acidosis)
39
Q

Metabolic Alkalosis

sxs:

A

confusion/increased DTRs/tetany/convulsions
hypotension/arrythmias
respiratory acidosis d/t decreased respiratory rate

40
Q

Ca+
(extracellular)
Fx/indications:

A

Provides strength & stability for skeletal system & serves as exchangeable source to maintain EC calcium levels. It plays role in many metabolic processes, including activity of enzyme systems, generation of action potential, & muscle contraction.

41
Q

Hypocalcemia

sxs:

A
paresthesias (esp numbness/tingling)
skeletal muscle cramps
abd spasms/cramps
increased DTRs
carpopedal 
laryngeal spasm
tetany
hypotension
s/o cardiac insufficiency
failure to respond to drugs that act by calcium-mediated mechanisms...osteomalacia, bone pain/deformities, & fx
42
Q

HYPERcalcemia

sxs:

A

polyuria/polydipsia
flank pain
s/o acute renal insufficiency/ s/o kidney stones
anorexia/N/V/constipation
muscle weakness/atrophy/ataxia/loss of muscle tone
osteoporosis
lethargy/personality & behavioral changes/stupor/coma
HTN/shortening of QT interval * AV block on EKG

43
Q

Na

values; nml/critical

A

Nml range 135-145 mEq/L

critical values <120 or >160 mEq/L

44
Q

Hypernatremia

causes:

A
diabetes insipidus
exc perspiration
copious diarrhea
impaired renal fx
decreased fluid intake
nephrotic syndrome
45
Q

Hypernatremia

(early) sxs:

A

dry, red, sticky tongue/mouth
restless
irritable

46
Q

Hypernatremia

(later) sxs:

A
delirium
twitching
sz
coma
increased muscle tone
hyperactive DTRs
metabolic acidosis
death
47
Q

Hypernatremia

txmt:

A

hypotonic saline solution (0.45%) NaCl
sodium restricted diet
lasix, HCTZ

48
Q

Hyponatremia

causes:

A
<136 mEq/L
extensive vomiting/diarrhea
Addison's dz
extensive burns
low-sodium diets, diuretic tx
increased water
renal failure
49
Q

Hyponatremia

(early) sxs:

A
thirsty
anorexia
abd cramping
confusion
lethargy
muscle twitching
50
Q

Hyponatremia

(late) sxs:

A

sz
loss of coordination
generalized weakness
coma

51
Q

Hyponatremia

txmt:

A

nml saline infusion
serum Na 2-4 hrs
daily weights

52
Q

K

values:

A

3.5-5 mEq/L

critical <2.5 or > 6.5 mEq/L

53
Q

Hyperkalemia

causes:

A
renal failure
acidosis
cellular damage w/ crushing injury
burns
other causes
54
Q

Hyperkalemia

sxs: (early)

A
cramps
muscle twitching
nausea
weakness
abd/genral
55
Q

Hyperkalemia

sxs: (later)

A

apathy
confusion
paresthesias
low, ascending paralysis lead to respiratory arrest
EKG changes
severe bradycardia
arrhythmias lead to 3rd degree heart block asystole

56
Q

Hyperkalemia

txmt:

A
monitor levels 4-6 hrs
monitor HR/rhythm
monitor I&O
restrict this electrolyte in diet
Kayexalate
lasix- K+ depletion
NaHCO3 (K+ moves into cells) - life threatening
57
Q

Hypokalemia

causes:

A
<3.5; critical < 2.5
excessive v/d
diuretics
DKA
TPN
Meds: geocillin; diamox; garamyan w/ CHG & chronic HTN
58
Q

Hypokalemia

sxs: (early)

A
muscle weakness
cramps
lethargy
apathy
drowsiness
confusion
irritability 
decreased bowel motility
cardiac abnormalities
59
Q

Hypokalemia

txmt:

A

IV or oral replacement
monitor this electrolyte lab q8 hrs
increase foods with this electrolyte

60
Q

Mg++

values:

A

1.3-2.1 mEq/L

critical values < 0.5 mEq/L or > 3 mEq/L

61
Q

Hypomagnesemia

causes:

A
alcoholism
malabsorption d/t colitis
cancer
hyperthyroidism
corticosteroid drugs
massive blood transfusion
62
Q

Hypomagnesemia

sxs: (early)

A
N/V/D/anorexia
muscle tremors
muscle twitches
agitation
irritability
63
Q

Hypomagnesemia

sxs: (late)

A

hyperactive DTRs
ataxia
vertigo

64
Q

Hypomagnesemia

sxs: (severe)

A
clonus
hallucinations
tetany
hypotension
nystagmus
coma/sz 
delirium
cardiac arrhythmias
CHF
65
Q

Hypomagnesemia

txmt:

A
increase this electrolyte in the diet
use antacids with this electrolyte 
MgSulfate IM/IV
serum level after q16 mEq
keep supine
handle pts gently
66
Q

Hypermagnesemia

causes:

A

renal failure
heavy use of antacids/laxatives
dialysis or TPN
hypoaldosteronism

67
Q

Hypermagnesemia

sxs: (early)

A
weak 
hypotensive 
flushed/hot 
absent DTRs
slurred speech
drowsiness
lethargy
cardiac arrthymias
68
Q

Hypermagnesemia

sxs: (later)

A
flaccid muscle
paralysis 
respiratory depression leading to coma
apnea
heart block
cardiac arrest
69
Q

Hypermagnesemia

txmt:

A

IV hydration
thiazide diuretics
calcium chloride or gluconate

70
Q

Phosphate (PO4)

values/critical:

A

3-4.5 mg/dL

critical values < 1 mg/dL

71
Q

Hypophosphatemia

causes:

A
malabsorption syndromes
colitis
shortened GI tract
excess thiazide
diuretics
72
Q

Hypophosphatemia

sxs: (early)

A
weakness
tissue hypoxia (disruption of cellular fx)
73
Q

Hypophosphatemia

sxs: (late)

A

mental confusion
irritability
severe anemia
bone brittleness (stress fx)

74
Q

Hypophosphatemia

txmt:

A

oral supplements
neutra soda
phospho-soda (now off-market bc contributed kidney issues)

75
Q

Hyperphosphatemia

causes:

A

renal failure

usually hypocalcemia concurrently

76
Q

Hyperphosphatemia

sxs:

A

sxs similar to hypocalcemia

77
Q

Hyperphosphatemia

txmt:

A

phosphate binders

restrict increased phosphate foods

78
Q

Calcium

values/critical

A

9-10.5 mg/dL
critical values < 6 (may lead to tetany)
critical values > 14 (may lead to coma/cardiac arrest)

79
Q

Hypocalcemia

causes:

A

malabsorption
parathyroid hormone deficiency
burns
copies wound drainage

80
Q

Hypocalcemia

sxs: early

A
numbness/tingling lips
anxiety/irritiability
twitching, cramps
grimacing
increased DTRs
81
Q

Hypocalcemia

sxs: late

A
bruising
impaired coagulation
general muscle spasms
gluconate
convulsion
cardiac arrhythmias
82
Q

Hypocalcemia

txmt:

A

Trousseau’s Phenomenon
Chyostek’s sign
monitor serum levels of this electrolyte
monitor EKG
diet rich in foods w/ this electrolyte & Vitamin D
this electrolye-gluconate or chloride

83
Q

+ Trousseau’s sign

A

carpopedal spasm that dev usually 2-5 min after applying & inflating BP cuff to ~20 mmHG higher than systolic pressure on upper arm. This spasm occurs as the blood supply to ulnar nerve is obstructed.

84
Q

Hypercalcemia

causes:

A
excessive use of milk/alkali products for peptic ulcer
multiple fx
multiple myeloma
renal failure
prolonged immobilization 
malignant growths
85
Q

Hypercalcemia

sxs: early

A
lethargy
depression/apathy
malaise/weakness
constipation
N/V
anorexia
diarrhea 
arrhythmias
86
Q

Hypercalcemia

sxs: (later)

A
HA 
coma
polydipsia
abd pain
flaccid paralysis
renal failure
renal calculi/polyuria
clumsiness
confusion/slurred speech/memory loss/stupor 
HTN
EKG changes
87
Q

Hypercalcemia

txmt:

A
IV fluids- isotonic saline
5-6 L 1st 24 hrs/3L/day thereafter
lasix
force fluids (cranberry
neutra phos/fleets
phospho-soda (may be off-market now d/t kidney issues)