Thyroid Lecture Flashcards
Thyroid gland location
Small saddle-shaped gland that wraps around the anterior portion of the trachea
Thyroid hormone regulates:
Metabolic rate heart function digestive function muscle control brain development bone maintenance
Used to produce hormones:
iodine
Serum TA Normal Value
Negative to 1:20
Serum TSH (sensitive assay) Normal value
0.35-5.5mU/mL
Serum T4 Normal Values
4.5-11.5 mcg/dL
Serum T3 Normal Values
80-200 ng/dL
T3 uptake Normal Values
25-35 relative percentage
Thyroid Suppression Findings in Hyperthyroidism
^ RAI uptake and T4 levels
Serum TA Test Findings in Hyperthyroidism
Increased
Serum TSH (sensitive assay) Findings in Hyperthyroidism
Decreased in primary hyperthyroidism
Serum T4 Findings in Hyperthyroidism
Increased
Serum T3 Findings in Hyperthyroidism
Increased
T3 Uptake findings in hyperthyroidism
Increased
Sympathetic Nervous System
fight or flight
Hyperthyroidism ________metabolic rate.
Increases
Hyperthyroidism is caused by an excessive delivery of_____.
thyroid hormone
Hyperthyroid_______SNS.
Increases
Hyperthyroidism Risk Factors
Women 10x Genetic Factors Family History of Graves ^ Iodine intake 20-40 age
Hyperthyroidism S/S
- ^ appetite w/ weight loss
- hypermotile bowels
- heat intolerance
- insomnia
- palpitations
- ^ sweating
- hair changes
Most common cause of hyperthyroidism
Graves Disease
Graves disease is an ______.
autoimmune disorder
Autoimmune disorder:
antibody in serum binds to TSH receptors in thyroid follicles causing hyperfunction
Goiter:
Enlarged thyroid gland in the neck
Graves disease S/S:
Exophthalmos eye pain blurred vision diplopia lacrimation photophobia
Graves Disease ^ risk of:
corneal dryness
irritation
infection
ulceration
Another most common hyperthyroidism
Toxic Multinodular Goiter
TMG develops:
slowly, usually in women in 60s and 70s
TMG:
small, independently functioning nodules