Thyroid Hormones

Question 1

What is another name for hypothyroidism?

Answer 1

Hashimoto disease

Question 2

What is another name for hyperthyroidism?

Answer 2

Graves disease

Question 3

Which hypothyroid medication is made from dessicated animal thyroid?

Answer 3

Armour Thyroid

Question 4

Composition ratio of T4 to T3 in Armour Thyroid?

Answer 4

T4:T3 is 4:1

Question 5

Is levothyroxine T4 or T3?

Answer 5

T4, so must be converted in the body to T3

Question 6

Is oral or IV formula preferred for Levothyroxine?

Answer 6

Oral

Question 7

T/F: Due to levothyroxine’s long half life, patient not necessary to be started on IV form immediately?

Answer 7

True

Question 8

After 7 days, what is the oral to IV dose conversion of levothyroxine?

Answer 8

1/2 oral dose is new IV dose

Question 9

Is there a T3 drug available?

Answer 9

Yes; Liothyronine or Cytomel

Question 10

How is liothyronine different than levothyroxine?

Answer 10

1. It is the levorotatory isomer of T3.
2. 2-3x more potent
3. Rapid onset/short duration
   4 More cardio side effects

Question 11

Is liothyronine or levothyroxine better for long-term thyroid replacement?

Answer 11

Levothyroxine

Question 12

Which hormone dose hypothalamus secrete?

Answer 12

Thryotropin releasing hormone (TRH)

Question 13

Which hormone does the pituitary gland secrete?

Answer 13

Thyroid secreting hormone (TSH)

Question 14

T/F: T3 and T4 work as negative feedback loop only to Pituitary gland no hypothalamus?

Answer 14

False; negative feedback loop to both hypothalamus and pituitary gland

Question 15

What is the oldest effective treatment for hyperthyroid?

Answer 15

Idoine

Question 16

What are adverse effects of antithyroid meds?

Answer 16

1. Transient leucopenia (can be significant)
2. Rash
3. Arthralgias
4. Lupus-like symptoms
5. Fever
6. Granulocytosis early in therapy

Question 17

Is liothyronine good for long term thyroid replacement?

Answer 17

No, b/c it has rapid onset and short DOA