Thyroid gland Flashcards
What are the expected resin uptake lab changes for hyperthyroidism? (T4 and T3 resin uptake)
elevated T4 and T3 resin uptake
What are the expected resin uptake lab changes for hypothyroidism? (T4 and T3 resin uptake)
decreased T4 and T3 resin uptake
What are the expected resin uptake lab changes for high TBG? (T4 and T3 resin uptake)
elevated T4
decreased T3 resin uptake
What are the expected resin uptake lab changes for low TBG? (T4 and T3 resin uptake)
elevated T3 resin uptake
decreased T4
What are the expected resin uptake lab changes for hepatic failure? (TBG and T3 resin uptake)
elevated T3 resin uptake
decreased TBG
What are the expected resin uptake lab changes for prengancy? (TBG and T3 resin uptake)
elevated TBG
decreased T3 resin uptake
What are the expected lab changes for primary hyperthyroidism? (TSH, T3/T4, special antibodies, and iodine uptake)
elevated T3/T4
decreased TSH
no special antibodies
increased iodine uptake
What are the expected lab changes for Graves’ disease? (TSH, T3/T4, special antibodies, and iodine uptake)
Caused by throid stimulating antibodies (form of primary hyperthyroidism)
elevated T3/T4
decreased TSH
thyroid stimulating Abs present
increased iodine uptake
What clincial feature (no antibody testing) can be used to differentiate non-Grave’s disease primary hyperthyroidism from Grave’s disease hyperthyroidism?
Exophthalmos, protrusion of the eyes from the orbit, is present in Grave’s disease
What are the expected lab changes for secondary hyperthyroidism? (TSH, T3/T4, special antibodies, and iodine uptake)
Caused by TSH-secreting pituitary tumor
elevated TSH and T3/T4
no special antibodies
increased iodine uptake
What are the expected lab changes for Hashimoto’s thyroiditis? (TSH, T3/T4, special antibodies, and iodine uptake)
Caused by antithyroid Ab (form of primary hypothyroidism)
elevated TSH
decreased T3/T4
antithyroid Ab present
decreased iodine uptake
What are the expected lab changes for iodine insufficiency? (TSH, T3/T4, special antibodies, and iodine uptake)
(form of pirmary hyporthyroidism)
elevated TSH
decreased T3/T4
no special antibodies present
?increased iodine intake
What are the expected lab changes for secondary hypothyroidism? (TSH, T3/T4, special antibodies, and iodine uptake)
Caused by decreased TSH secretion from pituitary
decreased TSH and T3/T4
no special antibodies
decreased iodine uptake
What thyroid pathologies result in goiter formation
Primary hyperthyroidism (Graves’ disease)
Secondary hyperthyroidism
Primary hypothyroidism (Hashimoto’s thyroiditis and iodine insufficiency)
