Thyroid Drugs Flashcards
1
Q
Synthetic T4
A
Use in hypothyroid
long half-life, QD
2
Q
Synthetic T3
A
Used less
short half-life, BID, TID
3
Q
KI
A
Rapid thyroid block to induce Wolff-Chaikoff
4
Q
PTU and methimazole
A
Inhibits TPO, methimazole has a longer half-life
PTU inhibits peripheral deiodination of T3/4
Methimazole is preferred except in pregnancy (aplasia cutis)
AE: maculopapular pruritic rash, hepatitis, agranulocytosis
