thyroid disorders Flashcards

(33 cards)

1
Q

what blood findings would you expect in hypothyroidism & myxedema

A

anemia, hyponatremia, hyperlipidemia, low FT4, and elevated TSH

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2
Q

what symptoms would you expect in hypothyroidism and myxedema

A

weakness, fatigue, cold intolerance, constipation, wt change, depression, menorrhagia, hoarseness

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3
Q

what signs would you expect to find in hypothyroidism and myxedema

A

dry skin, bradycardia, delayed return of DTR, menorrhagia, hoarsenes

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4
Q

would you expect to find the TSH level elevated or depressed in primary hypothyroidism

A

TSH should be elevated

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5
Q

T/F hypothyroidism may be due to failure or resection of the thyroid gland itself or deficiency of pituitary PTH

A

true or can be functional as in severe nonthyroidal illness

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6
Q

what are some drugs that can cause hypothyroidism

A

chemotherapeutic agents- radioiodine based, amiodarone (high iodine content), interferon

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7
Q

what is associated with an increased risk of autoimmune thyroiditis (antithyroid antibodies) leading to hypothyroid

A

Hepatitis C

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8
Q

what are 2 common syndromes seen in hypothyroidism

A

carpal tunnel and raynaud

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9
Q

what would hypothyroid look like

A

puffy face, eyes, frowzy hair, and dull apathetic appearance

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10
Q

how can hypothyroid affect your senses

A

decreased sense of taste, smell, and diminished auditory acuity

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11
Q

what is the single best screening test for hypothyroidism

A

serum TSH

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12
Q

over 95% of normal adults have a serum TSH under ___

A

3.0mU/L

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13
Q

what is the preferred Tx for hypothyroidism

A

synthetic levothyroxine

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14
Q

what is a complication of levothyroxine therapy

A

it can exacerbate HF in preexisting CAD

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15
Q

pts with severe hypothyroidism have an increased susceptibility to ___

A

bacterial pneumonia

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16
Q

what are some key symptoms of hyperthtroidism

A

sweating, wt change, anxiety, palpitations, loose stool, heat intolerance, irritability, weakness, menstrual irregularity

17
Q

what are some key signs of hyperthyroidism

A

tachycardia, warm moist skin, stare, tremor

18
Q

what are some key findings in Graves dz

A

goiter -often with bruit, opthalmopathy (exopthalamus/ proptosis, lid lag)

19
Q

in hyperthyroidism what would you expect to find hormonally

A

suppressed TSH in primary, inc T3,4 and FT3,4

20
Q

what is Graves dz

A

autoimmune disorder affecting the thyroid gland, characterized by an inc synth and release of thyroid hormone

21
Q

multiple autonomous toxic adenomas of the thyroid are seen in what Dz

A

toxic multinodular goiter

22
Q

subacute thyroiditis AKA “de Quervain or granulomatous” is typically caused by ___

A

viral infections

23
Q

what are some S/S of subacute throiditis

A

extremely painful thyroid, tender to touch, enlarged 3-4x, dysphagia and pain - can radiate to jaw or ear

24
Q

a high RAI uptake is seen in

A

Graves dz and toxic nodular goiter

25
a low RAI uptake is seen in
subacute thyroiditis
26
what are some complications of hyperthyroidism
hypercalcemia, osteoporosis, nephrocalcinosis, arrhythmias and HF
27
T/F propranolol is generally used for symptomatic relief of hyperthyroidism
true
28
how is toxic multinodular goiter treated
propranolol ER and methimazole
29
what autoimmune condition is the most common thyroid disorder in the US where B- lymphocytes invade the thyroid gland
Hashimoto thyroiditis
30
how does PTH maintain plasma Ca
by direct actions on kidney, bone and activating vit D
31
T/F bone is a calcium and phosphorus reservoir
true
32
in the kidney what effect does PTH have
inc Ca resorption; inc phosphate excretion; activates Vit D
33
does PTH inc or dec in low Ca and low Vit D
increase