Thyroid disorders Flashcards
Fill in the blanks with high, low or normal
In overt hyperthyroidism:
TSH is ________
T3 and T4 are _________
1) low
2) high
Fill in the blanks with high, low or normal
In sub clinical hyperthyroidism:
TSH is ______
T3 and T4 are _______
1) low
2) normal
What is the first line anti-thyroid drug
Carbimazole
Propylthiouracil if carbimazole unsuitable
What parameters need to be checked before starting an anti-thyroid drug
(2 points)
FBC and LFTs
Non drug treatment for hyperthyroidism?
2 points
Surgery or radioactive iodine
Can give anti-thyroid drugs while awaiting surgery
What drugs are used in the block and replace regimen for Graves’ disease?
(2 points)
Carbimazole and levothyroxine
Used for 12-18 months
True or false: carbimazole is safe in pregnancy
FALSE
Propylthiouracil is preferred
True or false: blood disorders can occur with anti-thyroid drugs
TRUE
If agranulocytosis occurs they should be stopped and treatment should not be restarted
Hypothyroidism or hyperthyroidism?
Signs include:
Weight gain with decreased appetite
Menstrual irregularities
Hair loss
Hypothyroidism
Fill in the blanks with high, low or normal
Overt hypothyroidism:
TSH is ______
T3 and T4 are ______
High
Low
Fill in the blanks with high, low or normal
Sub clinical hypothyroidism:
TSH is ______
T3 and T4 are ______
High
Normal
How long can is take TSH levels to return to normal after initiating levothyroxine ?
Up to 6 months
How often should TSH be measured during treatment with levothyroxine?
Every 3 months until stable then yearly
True or false:
Liothyronine is metabolised more rapidly than levothyroxine
TRUE
Remember:
Liothyronine = T3
Levothyroxine = T4
