Thyroid and Parathyroid Hormone Laboratory Flashcards
The most useful test for assessing thyroid function
THYROID-STIMULATING HORMONE
immunometric assays effectively screen for
hyperthyroidism
Second-generation TSH
chemiluminometric assays give fewer false-negative
results and more accurately distinguish between
euthyroidism and hyperthyroidism
Third-generation TSH
chemiluminometric assays give fewer false-negative
results and more accurately distinguish between
euthyroidism and hyperthyroidism
Third-generation TSH
exists providing a 10-fold increase in sensitivity
compared to third-generation assays
it is used primarily for research purposes
Fourth-generation assay
reference range for s-TSH
s 0.3–4.2 mIU/L
Measured by chemiluminometric assay or similar
immunometric technique
THYROXINE (T4)
reference range for T4
0.4–4.0 mIU/L
composed of both bound and free fractions
TRIIODOTHYRONINE (T3)
reference range for total T3
80–200 ng/dL
It is used as a second-line test after TSH in the evaluation of
suspected thyroid disorders and when used in conjunction with
TSH
FREE THYROXINE (FT4)
FT3 levels may be required to evaluate clinically euthyroid
patients who have an altered distribution of thyroid binding
proteins as seen during ____________ or in patients with
__________________.
pregnancy
dysalbuminemia
Reference range for FT3
2.8–4.4 pg/mL
LOW FREE T4
LOW TSH
Secondary
hypothyroidism
NORMAL FREE T4, LOW TSH
Subclinical
hyperthyroidism