Thyroid Flashcards

1
Q

Benign

A

Adenoma

- encapsulated in collagen

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2
Q

Malignant

A

Papillary
Follicular
Medullary
Anaplastic

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3
Q

Papillary

A
Most common 
Young adults 
Lymphatic spread
Usually solitary (Adeno)
Orphan Annie nuclei
Psommama bodies 
Mutations in RAS & BRAF
Good survival - lobectomy
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4
Q

Orhan Annie nuclei

A

Papillary thyroid cancer

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5
Q

Psommam bodies

A

Papillary thyroid cancer

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6
Q

Follicular

A
2nd most common 
Older (40-50)
Haematogenous spread 
Iodine deficiency, P13K AKT 
Invasive
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7
Q

Medullary

A

From c-cells that secrete calcitonin
Total thyroidectomy
Associated with MEN2

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8
Q

Anaplastic

A

Undifferentiated & aggressive
Involves neck structures causing death
Chemo & radio

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9
Q

Most common

A

Papillary

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10
Q

Most dangerous

A

Anaplastic

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