Thyroid Flashcards
Parathyroid
Function in the regulation of calcium metabolism
Thyroid Gland Function
To maintain optimal level of metabolism
TRH
Thyrotropin Releasing Hormone
TSH
Thyroid Stimulating Hormone
Organification
Inorganic Iodide enters thyroid follicles and is oxidized by the thyroid peroxidase and covalently bound to tyrosine residues.
T4
Major Circulating hormone but is four times less potent than T3
T3
Binds Nuclear receptors and acts a a transcription regulator
Primary Thyroid Gland Failure
95% of Cases
Secondary Hypothyroidism
No TSH secretion
Hashimoto’s Thyroiditis
autoimmune disorder, results from increased production of thyroid antibodies which destroys thyroid cells
Wolff-Chaikoff Effect
Iodine administration leads to HYPOthyroidism
Jod-Basedow phenomenon
Iodine administration leads to HYPERthyroidism
Hypothyroidism Features
Fatigue, weight gain, dry skin, cold intolerance