Thyroid Flashcards
High fT4
Low TSH
Primary thyrotoxicosis
Also: destructive thyroiditis, excess iodine intake, excess thyroid hormone
High FT4
Normal to High TSH
2ndary thyrotoxicosis
Normal FT4
Normal FT3
Low TSH
Subclinical hyperthyroidism
Normal FT4
High FT3
Low TSH
T3 toxicosis
High TSH
Normal ft4
Mild/subclinical hypothyroidism
High TSH
Low fT4
Primary/overt hypothy
Autoimmune hypothyroidism
Normal TSH, T4
Low fT3 and Total
Central hypothyroidism
Drugs/sick euthyroid syndrome
average daily replacement dose of levothyroxine is
1.6 µg/kg per day
Methimazole dose
PTU dose
propylthiouracil (PTU) (100–200 mg every 8 h initially, titrated to 50 mg once or twice a day
Thyroid storm Treatment
large doses of PTU (600-mg loading dose) should be admin-
istered orally, per nasogastric tube, or per rectum, followed 1 h later by five drops of saturated solution of KI (SSKI) q6h.
TSH level is low. T4 may be normal or minimally increased; T3 is often elevated to a greater degree than T4.
TOXIC MULTINODULAR GOITER
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A thyroid scan provides a definitive diagnostic test, demonstrating focal uptake in the hyperfunctioning nodule and diminished uptake in the remainder of the gland,
TOXIC ADENOMA