Thyroid Flashcards
Primary vs secondary thyroid
Primary - gland (t3, T4)
Secondary - hypothalamus/pituitary
Antibodies involved in Hashimoto thyroiditis
Antimicrosomal
Antithyroid peroxidase
Antibodies involved in Graves disease
TSH receptor antibodies
Most cost-effective investigation in the diagnosis of thyroid nodules for malignancy
FNAC
Which thyroid nodule could be more malignant, functioning/non-functioning
Non-functioning/Cold nodule
RAIU in graves, toxic nodule, thyroiditis, cold nodule
Functioning or non-functioning nodule differentiation
Increased uptake, diffuse - Graves
Increased uptake, one/multiple nodule - Toxic nodule
Dec uptake - Thyroiditis
No uptake - cold nodule
Radio iodine therapy will cause hypo/hyperthyroidism?
Hypothyroidism
Mcc of hypothyroidism
Hashimotos
TSH and T3 T4 in secondary hypothyroidism, next best investigation
Secondary means abnormality in pituitary/hypothalamus (central)
TSH - N or low
T3, T4 - low
Next best inv - MRI brain for tumours
Management of hypothyroidism
Thyroxine - 1.6 microgm/bodywt
Healthy elderly - 50 micrograms
Old, frail - 25/12.5 micrograms
Pregnancy and thyroid
Check TSH levels in first trimester
Iodine - 150micrograms/day for all
Mcc of b/l non-toxic goitre in Australia
Hashimotos thyroiditis
(hypo)
Anti-thyroid peroxidase antibody
Mcc of hyperthyroidism
Post partum hyperthyroidism»_space;
Graves disease
Plummers disease
Toxic multinodular goitre
Arrhythmias
CHF
Rx for hyperthyroidism in young, with small goitre, mild case
Propylthiouracil 200-600mg
or
Carbimazole
