thyroid

Question 1

Thryoid hormones

Answer 1

TRH ( stimulates pituitary) which goes to TSH.

TSH ( used for routine screening) which then tells the thyroid gland to poduce FREE T4.

t4- when levels of this increase in tells glands to stop producint tsh and trh - controls the feedback system. - acounts for most of thryoid hormone in system. usually monitor this as well.

t3 - converted from t4 - mor active form of hormone. monitor in hyperthyroid.

Question 2

low tsh in hyperthryoirism so then would want to check free t4

Answer 2

hypothyroidism - underactive - so when that happens - pituriarty releases a lot of TSH so will be high. and t4 will be low.

Question 3

hyperthryoidism

Answer 3

caused by

• graves
• anterior pituarity
• toxic nodulators
• amioderance

heat intolerance and tachycardia
weight loss.

Question 4

hyper treatment

Answer 4

anti thyroid drugs ( propylthiaouracil, methmazole

radioactive iodine

surgery

Question 5

hyper

Answer 5

antithyroid drugs ( thionamides)

commonly used in younger patients
- used for 1-2 years in treating graves to prevent relapse.
mild symtoms.

radioactive iodine
- indicated for older adults, cardiac patients, moderate to severe symptoms

Question 6

antithyroid agents

Answer 6

methimazol - preffered - not rec in pregnancy

propulthiouracil
- used in first trimester pregnancy and those who cant tolerate above med.

• not recc in kids - liver failure blaxk boc warning

blocks the synthesis of thyroxine and trii-

neither drug treats underlying issue. high relapse rates

goals of treatment to correct hypermetablic state, minimum adverse reactions, smallest incidence of hyporthyroism

any drug that produced bone marrow depression interacts - lithium, warfarin, pheno potassium, amiodarne

Question 7

adjunst therapy

Answer 7

beta blockers

• can reduce symptoms while you wait for other drugs to work

Question 8

hypothyroid

Answer 8

can be congenital
hashimotos,
iodine defiencys

pituitary or hypothalaimic failure
cushings

fatigure, cold, weight gain, constipation, dry skin, myalgia, menstural issues, hair loss, goiter, low heart rate, hypertension cool pale skin

Question 9

hypothyroid treatment

Answer 9

thyroxine ( t4) replacement
- take on empty stomach
- not with other meds,
repeat tsh in 6 weeks

dont give aftera cute mi, or thyrotoxicosis

pregnancy risk factor a and safe ith kids

symtpoms of hyperthyroidism

monitor bone density

interactions
— bile acid sequesterants, iron salts, antacids, may decrease warfarin, digoxin beta blockers

Question 10

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