thrombosis superimposed on atherosclerosis

Question 1

three factors that predispose to thrombosis:

Answer 1

1. edothelial injury
2. hypercoagulability
3. abnormal blood flow

Virchow’s triad

Question 2

abnormal blood flow

Answer 2

stasis and turbullence

Question 3

stasis

Answer 3

much more of a problem in veins than arteries except where arteries have localized outpouching (aneurysm)

Question 4

turbulent flow

Answer 4

occurs over atherosclerotic plaques

Question 5

what can release thrombogenic material into blood stream?

Answer 5

plaque erosion or rupture

Question 6

What is more likely to cause thrombosis in younger pts, especially women?

Answer 6

erosion

more likely to make it to organizing phase

Question 7

What is thrombosis due to plaque rupture most likely to proceed to?

Answer 7

100% occlusion of artery

Question 8

importance of this in atherosclerotic CV disease is what makes ___ and ___ important components of treatment and prevention

Answer 8

aspirin and clopidogrel (Plavix)

Question 9

Thrombosis superimposed on rupture of a coronary atherosclerotic plaque is especially likely to lead to…

Answer 9

total occlusion and transmural (full thickness) MI