Thrombosis and AC 2 Flashcards

1
Q

Risk factors for SVT progressing to DVT (3)

A

Large clot (>5 cm)
Proximity (<5cm) to saphofemoral or saphenopopliteal junction
Medical RFs (Malignancy, estrogen, prior DVT)

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2
Q

Management of low risk SVT

A

Supportive care

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3
Q

Management of high risk SVT

A

Therapeutic AC for 45 days to 3 months

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4
Q

management of intermediate risk SVT

A

Prophylactic anticoagulation for 45 days

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5
Q

What imaging study should be ordered after diagnosing someone with an upper extremity DVT?

A

CXR to look for bony abnormalities

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6
Q

Management of someone with upper extremity DVT with moderate-severe acute symptoms

A

Thrombolysis + anticoagulation for 3 months
maybe thoracic outlet decompression

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7
Q

Management of upper extremity DVT in someone with a delayed presentation

A

AC for 3 months
Thoracic outlet decompression

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8
Q

Management of acute Portal Vein Thrombus in the setting of a transient thrombotic risk factor like pancreatitis.

A

AC for 6 months

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9
Q

What is May-Thurner syndrome?

A

External compression of IVC leading to increased risk of thrombosis

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10
Q

Management of May-Thurner syndrome without DVT but moderate-severe symptoms

A

Angioplasty and stent

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11
Q

Patient presents with flank pain, hematuria, significant AKI, and renal infarction on biopsy. Labs show markedly elevated LDH. Diagnosis and management?

A

Renal vein thrombus
Thrombolytic therapy +/- thrombectomy

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12
Q

Patient with nephrotic syndrome presents with renal vein thrombus but there is no AKI. Management?

A

Anticoagulation for 6-12 months or however long they are nephrotic

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13
Q

What are two options for VTE prophylaxis after completion of therapeutic anticoagulation?

A

Aspirin
Rivaroxaban

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14
Q

Which DTI does not have to be dose-adjusted for renal failure?

A

Argatroban

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15
Q

Which DTI is oral?

A

Dabigatran. Needs parental AC overlap

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16
Q

Least renally cleared DOAC

A

Apixaban

17
Q

DOACs are preferred for acute VTE treatment in patients with cancer, with what exception?

A

GI/GU cancers

18
Q

Reversal of warfarin for a patient with INR <4.5 and no bleeding

A

Hold warfarin

19
Q

Reversal of warfarin for a patient with INR 4.5-10 and no bleeding

A

Hold warfarin
Consider oral Vitamin K if high bleeding risk

20
Q

Reversal of warfarin for a patient with INR >10 and no bleeding

A

Hold warfarin
Oral Vitamin K 2.5-5 mg daily

21
Q

Reversal of warfarin for a patient with INR >2 and life-threatening bleed

A

Hold warfarin
IV Vitamin K 10 mg
4 factor PCC or 3 factor PCC + FFP

22
Q

Reversal agent for DOACs

A

Andexanet alpha

23
Q

Reversal agent of dabigatran

A

Idarucizumab