Thrombophilias Flashcards
1
Q
Which thrombophilia is most severe?
A
Antithrombin III deficiency
70-90% lifetime risk
Pregnancy thrombosis risk: 60%
2
Q
What is VTE risk with heterozygous Factor V?
A
5x increase
3
Q
What is VTE risk with homozygous Factor V?
A
80x increase
4
Q
What is lifetime clot risk of Protein C def?
A
50%
In pregnancy, 10-30%
5
Q
What blood tests are part of the diagnostic workup for antiphospholipid antibody syndrome?
A
anticardiolipin Abs (IgG and IgM)
anti B2 glycoprotein (IgG and IgM)
Lupus anticoagulant
