Thromboembolism

Question 1

Types of Venous (returning to the heart) Embolism

Answer 1

DVT

Pulmonary Embolism

Question 2

Virchow’s Triad

Answer 2

Stasis (i.e. bed rest)
Endothelial damage (i.e. trauma, central line)
Hypercoagulability (i.e. cancer, pregnancy)

Question 3

Partial Thromboplastin Time (PTT)

Answer 3

• Measures pathway for clot formation
• measures how fast blood clots
• Normal value: 60- 70 seconds
• Tracks with IV Heparin

Question 4

Activated Partial Thromboplastin Time (APTT)

Answer 4

• activators added to PTT to shorten normal clotting time and provide a more narrow normal range
• Quicker than PTT
• Normal Value: 30- 40 seconds
• Tracks with IV Heparin

Question 5

Prothrombin Time (PT, Protime, International Normalized Ratio (INR)

Answer 5

• evaluates the mechanisms for clotting.
• Normal values PT: 11.0-12.5 seconds (depends on reagents)
• tracked by warfarin

Question 6

International Normalized Ratio (INR)

Answer 6

• gives HCP’s from around the world the ability to report uniform prothrombin time (PT) results without respect to methods or reagents.
• Normal values INR: 0.8-1.1