Thrombocytopenia in the Peds...DO SARAH GILLENS FLASHCARDS ON THIS

Question 1

Bleeding risk for a given platelet count of 150,000-450,000 uL

Answer 1

normal hemostasis

Question 2

Bleeding risk for a given platelet count of <75,000 uL

Answer 2

primary hemostasis is impaired

Question 3

Bleeding risk for a given platelet count of <50,000 uL

Answer 3

Spintaneous bleeding is possible

Question 4

Bleeding risk for a given platelet count of <20,000 uL

Answer 4

Clinically significant bleeding possible

Question 5

Bleeding risk for a given platelet count of < 10 uL

Answer 5

life threatening hemorrhage possible

Question 6

The goal in management of thrombocytopenia is to keep platelets at or above ____

Answer 6

20,000 uL

Question 7

Name the four “umbrella” categories for causes of thrombocytopenia.

Answer 7

1. decresased production of platelets
2. sequestration of platelets (in the spleen)
3. increased destruction of platelets (immune or non-immune)
4. platelet loss or dilution

Question 8

Develop a differential diagnosis of children with acute thrombocytopenia.

Answer 8

j

Question 9

Identify the clinical findings consistent with thrombocytopenia.

Answer 9

• petechiae
• purpura
• gingival bleeding
• epistaxis
• menorrhagia
• GI bleeding
• hematuria
• CNS hemorrhage
• ecchymosis/bruises
  
  • worry if:
    
    • multiple
    • atypical distribution
    • bruising inconsisent with activity or force of injury