Thrombi, emboli and coagulation Flashcards
1
Q
What are the two main reasons clots don’t form all the time?
A
Laminar flow - cells generally don’t touch the vessel walls (they flow down the middle)
Endothelial cells aren’t ‘sticky’ when healthy
2
Q
What are venous thrombi most likely to cause? arterial thrombi?
A
Venous thrombi - PE
Arterial thrombi - heart attack / stroke
3
Q
Give three examples of less common causes of emboli?
A
air
cholesterol crystals
tumour
4
Q
Four general steps of clotting?
A
5
Q
Give the classes of drug used to treat i) arterial thrombosis ii) venous thrombosis
A
Arterial Thrombosis- Anti-Platelets e.g Aspirin/Clopidogrel (1)
Venous Thrombosis- Anti-Coagulants e.g Warfarin, Heparin, NOAC (1)
6
Q
what blood test can test for DVT?
A
7
Q
why is the D-dimer blood test for DVT not very specific?
A
