Thomas Schwartz Book Chapter 8 summary

Question 1

Comorbidity with schizophrenia psychosis

Answer 1

1. 15% panic disorder
2. 29% PTSD
3. 23% OCD
4. 50% MDD
5. 47% substance use disorder

Question 2

Schizophrenia Spectrum

Answer 2

1. brief psychotic disorder- lasts a month or less and has no negative schizophrenia psychosis (SP) symptoms.
2. schizophreniform disorder- lasts 1-6 months with full SP symptoms.
3. schizophrenia- lasts greater than 6 months with full SP symptoms.
4. delusional disorder- only has delusions but never has hallucinations, thought disorder, or negative symptoms.
5. schizoaffective disorder- meets full SP criteria while predominantly experiencing MDD or bipolar as well.

6.

Question 3

Prescribing tips (p. 293)

Answer 3

1. antipsychotics are essential to alleviate psychotic symptoms.
2. best to use a medication that can safely treat SP over a longer duration as SP is most often life long.
3. Psychoeducation to patient and significant others (when possible).
4. CBT and family therapy can lower the risks of relapse risk.
5. 1st and 2nd generation antipsychotics carry significant risks.

Question 4

Epidemiology, Genetics, and Neuroanatomy (pp 297-298 of Schwartz book.

Answer 4

1. schizophrenia affects 1 in 100 folks.
2. affects men and women equally but recent data suggest men are more affect at 1.4:1.
3. account for the largest expense in healthcare agencies
4. 24-55% heritability.
5. SP brain can develop tissue atrophy and ventriculomegaly
6. neurodevelopment abnormalities in brain symmetry.

7.