Third year Flashcards

Question

Sevelamer

Answer 1

A

It is an anti-arrhythmic
It is used to control an irregular or rapid heart rate
Patients take one daily dose of 200mg after a reduced titration dose
It takes about 1-30 minutes for duration of action when given iv
Avoid grapefruit anD st.John’s wort when taking this medication
Take the medication with food or without
Serious side-effects include bradycardia, hypotension, hypothyrodism or thyrotxicosis due to it binding to the thyroid receptor as it contains ionic content.

Answer 2

A

This is a tricyclic antidepressant indicated for the treatment of depressive illness., psychotic episodes, and depression associated anxiety also used in the treatment of migraines.
2. Amitriptyline works by inhibiting the membrane pump that is responsible forthe re-uptake of neurotransmitters like norepinephrine and serotonin. Therefore increases there concentrations in the brain.
3. Avoid alcohol whilst on this medication
4. It can take up to two weeks for the patient to feel better and 4-6 weeks for the maximum effect to be felt.
5. Best to take amitriptyline before going to bed or in the evening as it can cause sleepiness.
6. Ca n take with or without food. Swallow tablets with a fladd of water.

If you take Amitriptyline OD and miss a dose, skip that dose and resume at usual tiem for the next day. If you take it three times or 2 times a day. Then take the missed dose as soon as you remember, however skip that specific missed tablet if you remember close to the time you are do the other normal scheduled tablets,

8.NEVER take TWO doses at the same time.

Common side-effects of the drug that means you sitll continue taking medication whilst simultaneously speaking to your GP
:

Constipation
Dizziness
Fatigue and sleepiness
Difficulty peeing
*Headaches

Serious side-effects
* Irregular or fast heartbeat
* Yellow eyes from white
* Long lasting confusion
* Weakness
* Constant headaches
* Muscle cramps -this indicates a low level of salt in the body which can cause for convulsions and fits
* Sucidal thoughts
*Eye pain or swelling or redness in or around your eye
* Long lasting constipation

Call 999 and ask for an ambulance if:
you have weakness on one side of your body
you have trouble speaking or thinking
you lose your balance or have blurred eyesight

Answer 3

A

This is a prodrug of mercaptopurine
Azathioprine is used in order as an immunosuppresant in RA or SOD therapy or transplant.
This drugs works by causing for T-cell apoptosis. Also works by inhibiting the synthesis of purines which means t-cells and B-cells are inhibited.
Toxicity includes
* Hepatoxicity
* Bleeding
*Infection
* Bone marrow hypoplasia
*
Azathioprine NEEDS to be taken WITH FOOD. as it causes for GI disturbances.
Common side-effects causes for mild nausea and the feeling of sickness,

Answer 4

A

It is an anti-depressant
Drug family is the ‘‘selective serotonin-reuptake inhibitors’‘(SSRIs).
Citalopram works by enhancing the levels of serotonin in the brain by inhibiting serotonin reuptake.
Citalopram is considered to be one the best SSRIs for the treatment of depression because it is very selective, and has a very small effect on dopamine and norepinephtine transportation. It also does not bind to the muscarinic receptors. Less side-effects.