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PHAR 124 > Things we should just know > Flashcards

Things we should just know Flashcards

1
Q

What are the two natural Gelling agents

A

Alginic Acid
Tragacanth

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2
Q

What are the two semi-synthetic- cellulose derivatives (Type of gelling agents)

A

Methylcellulose (Runny)
HPMC (Thicker, time release)

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3
Q

What are the synthetic Gelling agents

A

Carbomers *Neutralizer, Thickener
Poloxamers Absorbing, mostly pharmacy compound **Reverse thermal

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4
Q

What does the DLVO theory describe?

A

Estimating the stability of hydrophobic solutions

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5
Q

With regard to DLVO theory what forces of attraction predominates the repulsive forces?

A

Small distance (Primary minimum) and long distance (Secondary attraction)

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6
Q

Three ways of stabilizing a dispersed system

A

Change viscosity
Add buffer to maintain stability
Add Electrolytes for compatibility

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7
Q

What are the external phase Polar Liquids (Medium)

A

Water, Simple Syrup, Cherry

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8
Q

What are the external phase non-polar liquids (Medium)

A

Oils,Fatty Esters, hydrocarbons

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9
Q

What are the properties of structured vehicles in solutions? (High and low concentration)

A

They serve as protective colloids at low concentration while at high concentrations they are viscous inducing agents

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10
Q

What are the three flocculating agent categories we discussed with regards to suspensions

A

Electrolytes
Ionic Surfactants
Polymeric flocculating agents

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11
Q

What is an issue with the usage of polysaccharides as a viscosity modifier?

A

They increase the susceptibility to microbial growth

Acacia gum
Tragacanth
Alginates

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12
Q

What are the water soluble cellulose derivatives viscosity modifiers?

A

Methylcellulose
Microcrystalline cellulose

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13
Q

What are the Hydrated silicates viscosity modifiers?

A

Bentonite

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14
Q

What are the Acrylic acid polymer viscosity modifiers?

A

Carbopol/Carbomer

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15
Q

What are the inorganic Colloids?

A

Milk of magnesia Two phase system

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16
Q

What are the organic colloids?

A

Single phase system,Carbomer

17
Q

What is alginic acid?

A

Natural gelling agent that is prone to microbrial growth,

18
Q

What is Tragacanth?

A

Natural gelling agent that is used fora stable PH

19
Q

What is Methylcellulose?

A

Semi-synthetic cellulose derivative that maintains viscosity over wide ph range,

This makes thinner gels htough and hydrates in HOT water

20
Q

What is HPMC?

A

Makes thick boi gels
Semi-synthetic cellulose derivative gelling agent

21
Q

What is Carbomers or Carbopol?

A

Synthetic gelling agent that thickens AND requires PH neutralizers

When it gets thick it gets ph spicy

22
Q

What is Poloxamers?

A

Synthetic gelling agent that forms reverse thermal gels!

23
Q

What are colloidal gold, sulfur, and silver examples of?

A

Lyophobic colloids

24
Q

What are the 5 Viscosity modifiers for suspensions?

PWHAC

A

Polysaccharides
Water soluble cellulose derivatives
Hydrated Silicates
Acrylic acid polymers
Colloidal silicin dioxide

25
Q

Types of bioreactors

A

Liquid and solid state

26
Q

Low concentrations of phospholipids and surfactants have been shown to?

A

Extert a fibrillation-inhibitory effect

27
Q

What is the sweeter than sucrose value for cyclamate?

A

30 times

28
Q

What is the sweeter than surcose value for saccharin?

A

300x

29
Q

What is less sweet then sugar?

A

Sorbitol, mannitol, aspartame

30
Q

What is the sweeter than sucrose value for stevia?

A

200x

PHAR 124 (6 decks)

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