Therapeutics Exam 3 (Pediatric Nutrition) Flashcards
What are the 5 nutrition basics of infants?
-Lack of caloric reserve
-Increased metabolic rate
-Higher growth rates
-Increased demands during illness
-Dependent on others for nutrition
How does the metabolic rate of infants compare to adults?
It is higher
-they have much higher nutritional needs
What is the typical weight range for an infant at birth?
3-4 kg
The weight of an infant doubles from their birth weight by how many months?
4-6 months
The weight of an infant triples from their birth weight by how many months?
12 months
By 12 months, an infant’s length increases by what percent?
50%
Adipose tissue distribution begins after what age?
age 2
(fat stores increase)
How do you decide whether to use the WHO growth chart or the CDC growth chart?
WHO: <2 years old
CDC: 2-20 years old
True or False: Growth is a linear process
FALSE
Multiple factors affect growth:
-Age
-Organ function
-Body composition
What organ in neonates requires the most energy to function?
Brain
What percent of a neonate’s basal energy expenditure is used by their brain?
50%
What is malnutrition?
Deficiencies or Excesses in nutrient intake
Imbalance of essential nutrients
Impaired nutrient utilization
What is a Z-score?
A statistical analysis that tells us the distance and direction of an observation from a population mean
(ex: -4 would be 4 standard deviations lower than the population mean)
What 2 factors may indicate that a pediatric patient is experiencing failure to thrive (aka growth faltering)?
-They fall down 2 major percentiles in growth
-Weight <3rd-5th percentile
What are the 3 causes of malnutrition?
Inadequate caloric intake
Inadequate absorption
Excessive energy
How many kcal are in breast milk?
20 kcal/oz
Which percentile do we use on a growth chart if we want to find an average?
50th (right in the middle of the percentiles)
What are the breast feeding recommendations by AAP and WHO?
AAP: Exclusive breast feeding for first 6 months, optimally continue for 1 year, may extend beyond 1 year if desired
WHO: Suggests up to 2 years
What are the contraindications to breast feeding?
**HIV positive
DRUGS (elicit and non-elicit)
What are the 2 broad categories that drugs to avoid during breastfeeding fall into?
Drugs that can harm the infant directly
Drugs that reduce milk production
Which drugs can harm the infant directly?
Immunosuppressants
Chemotherapy
Radioactive agents
Which drugs reduce milk production?
Ergots
Decongestants
Antihistamines
What drug characteristic makes a drug more likely to be absorbed by the infant while breastfeeding?
High oral bioavailability
What drug characteristics increase the level of a drug in breastmilk?
Non-ionized
Small Molecular Weight
Low Protein Binding (free floating)
High Lipid Solubility (lots of fat in breast milk)
Long T1/2 (sticks around longer)
Low Vd (not bound to many things, free floating in blood stream, get delivered to breastmilk via blood)