Therapeutic index Flashcards

1
Q

What is the therapeutic index

A

It is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes toxicity

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2
Q

Purpose of the therapeutic index

A

measurement of the relative safety of a drug.

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3
Q

More concern: Broader or Narrow TI

A

Narrow

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4
Q

Two example drugs of narrowing TI

A

Warfarin, Digoxin

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5
Q

Level to be measured with Warfarin

A

INR

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6
Q

Level to be measured with Digoxin

A

Digoxin

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