Theory Flashcards
Garre’s sclerosing osteomyelitis
Chronic disease affecting the mandible secondary to minor chronic odontogenic infection
Presentation: swelling, non-suppurative, +/- pain, local inflammation (accompanied by pain + thickening of underlying bone (high osteoblastic activity))
Mostly teens <20
Treatment: removal of infection source
Differential dgn: Ewing’s sarcoma or osteosarcoma
Infantile osteomyelitis
Hematogenous
Caused by perinatal trauma, maxillary sinusitis or infected nipple
Staphylococcus aureus
Can lead to sepsis
Premalignant oral lesions
Erythroplakia
Oral leukoplakia
Submucous fibrosis
Lichen planus
Benign tumors oral
Lipoma
Fibroma
Papilloma
Inflammatory fibrous dysplasia
Non-opioids
More potent than opioids for inflammatory pain
Antipyretic/antifever
Paracetamol dosage?
500mg every 4-6h
Children 10-20 mg/kg QID
Max: 4000mg
Preferential cox-1 inhibitors?
aspirin, ketoprofen
Non-selective cox 1&2 inhibitors?
ibuprofen
naproxen
diclofenac
lornoxicam
preferential cox-2 inhibitors?
meloxicam
numesulide
aceclofenac
selective cox-2 inhibitors?
celecoxib
etoricoxib
Drugs administered every 12h?
Naproxen
nimesulide
aceclofenac
celecoxib
Drugs administered every 4-6h?
Aspirin
Ketoprofen (3-4h)
ibuprofen
acetaminophen/paracetamol
Drugs administered every 8h?
Dexketoprofen? (3x/day)
diclofenac
lornoxicam
metamizole
Which NSAIDs cause significant GI toxicity & have antiplateled action?
preferential cox-1 inhibitors
Contraindicated in pregnancy?
opioids
aspirin
preferential cox-2 inhibitors
selective cox-2 inhibitors