Theoretical Genetics

Question 1

Explain the consequence of a base substitution mutation in relation to the processes of transcription and translation, using the example of sickle-cell anemia.

Question 2

Define Genotype

Question 3

Define Phenotype

Question 4

Define Dominant Alelle

Question 5

Define Recessive Alelle

Question 6

Define Co-dominant alelle

Question 7

Define Locus

Question 8

Define Homozygous

Question 9

Define heterozygous

Question 10

Define Carrier

Question 11

Define Test Cross

Question 12

State that meiosis is a reduction division of a diploid nucleus to form haploid nuclei.

Question 13

Outline the process of meiosis, including pairing of homologous chromosomes and crossing over, followed by two divisions, which results in four haploid cells.

Question 14

Explain that non-disjunction can lead to changes in chromosome number, illustrated by reference to down syndrome(trisomy21).

Question 15

Determine the genotypes and phenotypes of the offspring of a monohybrid cross using a Punnett grid.

Question 16

State that some genes have more than two alleles(multiple alleles).

Question 17

Draw the structure of a Nucleotide DNA.