Theme I Flashcards

1
Q

Per gram, how much energy does fat, carbohydrate, protein and alcohol give you

A
  • Fat= 9kcal/ g
  • carb= 4kcal
  • protein= 4kcal
  • alcohol= 7kcal
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2
Q

What is the estimated average requirement for energy nutrients and what it depends on

A
  • Average intake needed for a healthy individual to maintain their energy balance (without losing or gaining weight)
  • Depends on age, sex, weight, height, BMR, level of physical activity, growth
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3
Q

What is BMR and BMI and the mean values. How to calculate energy requirement for an individual

A
  • BMI= weight (kg)/ height (m) squared
    (18. 5-24.9)
  • BMR= basal metabolic index-=energy required for body to function (heart beating, breathing, brain function)
  • women= 1400 calories daily
  • men= 1800 calories

-requirement= BMR x physical activity level

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4
Q

Function of fat. What are the 3 types of fat and their sources

A
  • Good source of energy, precursor of prostaglandins, reduces inflammation, required for absorption of fat-soluble vitamins (ADEK)
    1. Saturated= no double bonds between Carbons in FA chain. Bad fat, increases LDL and decreases good HDL. Dairy products
    2. Monosaturated= 1 double bond. VERY good because decreases cholesterol. Olives and nuts
    3. Polysaturated= >1 double bond. Plant oils, fish oils. Good. Liquid at room temperature
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5
Q

Explain what the essential fatty acids are

A
  • Linoleic (omega 6) and linolenic (omega 3) fatty acids - usually PUFA
  • Plant and fish oils
  • Form prostaglandins, reduce platelet aggregation, reduce thrombosis
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6
Q

Explain what cis and trans

A
  • unsaturated.
    1-Cis=H atoms are linked to the double bonded Cs on 1 side. Found in nature

2-Trans= H atoms are linked on one side
-in hydrogenated oils used by manufacturers to keep food fresher for longer. But it increases LDL and linked with CVD and colon cancer

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7
Q

What are used in a cholesterol low diet, to reduce cholesterol absorption

A
  • Plant sterols and plant stanols: prevent cholesterol absorption, lower LDL. In fruits, veg, nuts, seeds, cereals
  • Oat fibre: reduces absorption by binding to it
  • soya protein in soya milk and tofu
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8
Q

What are carbohydrates. Food sources. How much energy you should get from it

A
  • 50% of total energy should come from carbs
  • Sugars, starches and oligosaccharides
  • starch= potatoes, cereals, bread, pasta, rice
  • sugars= confectionary, sugary drinks, table sugar, biscuits, preserves, cake etc.
  • fibre= fruit, veg
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9
Q

What are monosaccharides, disaccharide and oligosaccharides. Give examples

A
  • Monosaccharide= 1 sugar molecules (glucose, fructose, galactose)
  • Disaccharides = 2 sugar molecules (sucrose, maltose, lactose)
  • Oligosaccharide= 3+ sugar molecules. Not classed a sugars so manufacturers can be sneaky. They are polysaccharides. Don’t seem to cause caries
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10
Q

What are free sugars. Why they are bad

A

-Sugars that have been added to food, as well as sugars in syrups, honey, fresh fruit juice and fruit juice concentrates
(Sugars in fruit are not free sugars as they are intrinsic and contained within a cell. But when you juice it, then you break down the cell and release the sugar and it becomes a free sugar/ extrinsic)
-Should only eat 30g per day

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11
Q

What is starch. How much energy should it provide but how much do we get

A
  • A polysaccharide made of glucose monomers joined in alpha 1,4 linkages. [Amylose + amylopectin]
  • potatoes, cereals, bread, pasta
  • It is about 24% but should be at least 30%
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12
Q

Protein functions, requirement, sources, calculating requirement

A
  • Growth repair, energy, maintenance of tissue, hormones and enzymes.
  • Sources from meat, fish, dairy products, veg, quoin, nuts, soya
  • Amount required is the amount needed to be in nitrogen balance (nitrogen input=output)
  • About 12% of total energy
  • About 0.75-1.5 g per kg of body weight
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13
Q

The 3 types of protein deficiencies an the disease and symptoms they cause

A
  1. Protein-energy: Marasmus - severe muscle wasting, decreased insulin, oedema
  2. Protein: Kwashiokor- energy maintained but protein is deficient causing high insulin, oedema
  3. Malnourished: NOMA - ulcerating stomatitis of upper gum, ulceration of cheeks
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14
Q

What is fibre. Sources. Functions. Rough intake per day

A
  • Found in whole grains, fruit, veg, legumes, nuts, and it cannot be broken down by the body
  • Increases faecal mass
  • Lowers risk of cardio-metabolic disease, colo-rectal cancer, lowers BP and cholesterol
  • 30 g per day
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15
Q

What is a vitamin. Differences between water soluble and fat soluble vitamins and give examples

A
  • Vitamins are organic substances required in small amounts. Absence leads to a deficiency disease
  • Water-soluble= not stored well, needed regularly, generally not toxic in excess. B and C
  • Fat soluble= stored, not absorbed or excreted easily. ADEK
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16
Q

Thiamin (B1): sources, function, deficiency, oral relevance, requirements

A

*All B vitamins act as co-enzymes in metabolic pathways

  • whole grain, pork, poultry, fish , veg, dairy
  • 0.5mg
  • glucose metabolism

-Deficiency= cardiovascular problems, memory loss,

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17
Q

Riboflavin (B2) sources, function, deficiency, oral relevance, requirements

A
  • milk, protein-bound,
  • aids in release of energy from proteins
  • FAD, redox reactions, blood production, body growth
  • deficiency rare, except in alcoholics. Causes angular stomatitis
  • not toxic in excess
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18
Q

Niacin: sources, function, deficiency, oral relevance, requirements

A
  • cereals, wheat, rice
  • NAD and NADP redox reactions
  • lowers plasma lipid
  • deficiency= pellagra (dermatitis, diarrhoea, dementia)
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19
Q

Pyridoxine (B6): sources, function, deficiency, oral relevance, requirements

A
  • Beef liver.Tuna.Salmon.Fortified cereals.Chickpeas.Poultry.
  • amino acid metabolism
  • synthesis of serotonin, NA, haem
  • treats seizures
  • used in Down’s syndrome and autism
  • deficiency usually caused by antagonists for diseases that increase requirements - tuberculosis, rheumatoid arthritis etc. So given supplements
  • toxicity causes peripheral neuropathy
20
Q

Why alcoholics may suffer vitamin deficiencies

A
  • They may have adequate energy intake but this may be regarded as empty calories from alcohol, with inadequate levels of vitamins and nutrients.
  • GI tract malfunctions
  • Cirrhotic liver which affects storage, transport and metabolism of vitamins
  • Stroage and transport of fat-soluble vitamins may be impaired.
21
Q

Folate: sources, function, deficiency causes and signs, requirements

A
  • mainly in green veg, liver and whole grains
  • 50ug
  • carrier of 1-C fragments in amino acid synthesis (methionine) and DNA synthesis (deoxyuridylic acid to deoxythymidylate) for example
  • deficiency due to poor diet, low levels of greens, alcoholism. Causes tiredness, blurred vision, pins and needles, confusion (same as B12) Causes neural tube defects
22
Q

Vitamin B12: sources, function, deficiency causes and signs, requirements, absorbance

A
  • a carrier of methyl groups in metabolism.
  • a cofactor in DNA synthesis (homocysteine to methionine). Needed in fatty acid metabolism, and amino acid metabolism (methyl-malonyl CoA to succinylcholine-CoA).
  • only present in animal tissues
  • it binds to intrinsic factor secreted by gastric cells to allow for absorption and transport. Lack of intrinsic factor most common cause of pernicious anaemia.
  • absorbed in small intestine
  • 1 ug required daily
  • Vegan diets provide no B12 so risk of deficiency. Signs include tiredness, anorexia, megaloblastosis, anaemia. Neurolgical changes such as numbness, moodiness due to lesions and inadequate myelin synthesis.
23
Q

Pantothenic acid: sources, function, deficiency

A
  • Small amounts in a wide range of foods
  • component of co-enzyme A that transfers carbon chains (eg. in fatty acid oxidation)
  • Deficiency rare
24
Q

Biotin: sources, function, deficiency, requirements

A
  • peanuts, chocolate, egg yolk. Made in intestinal bacterial synthesis
  • prosthetic group for carboxylations. (pyruvate carboxylases, acetyl CoA to malonyl CoA)
  • deficiency rare in normal diet. Except diets with raw eggs and wine. Also, long term antibiotic therapy as it sterilises the GI tract
25
Vitamin C (ascorbic acid): sources, function, deficiency cause and signs, oral relevance, requirements
- citrus fruits, tomatoes, berries, kiwi (most fruit and veg) - anti-oxidant. Helps iron and folate absorption. Tissue repair, forming collagen, producing neurotransmitters. - deficiency= usually in elderly, alcoholic and smokers (turnover of Vit C is greatly increased by smoking) Causes scurvy
26
Vitamin A: sources, 3 different active forms and functions, deficiency, toxicity
- liver, milk, egg yolk, veg and fruit - Retinoic acid- acts as a hormone, controlling protein synthesis - Retinal - for vision - B carotene - antioxidant - deficiency rare but more common in developing countries, associated with inadequate protein diets. - toxicity= dermatitis, hair loss, mucous membrane defects, hepatic dysfunction, red gums, thinning and fracturing of long bones
27
Vitamin E: sources, most potent form, function, deficiency, overdose
- vegetable oils, nuts, green veg, seeds - alpha tocopherol the most potent - antioxidant. Prevents oxidative damage of polyunsaturated FAs. Enhances immune function. Gathers harmful free radicals in the body. - deficiency unlikely as easy to get in diet. But may be caused if fat absorption is impaired in diseases such as pancreatitis. causes premature babies. Causes haemolytic anaemia. Weakened immune system. Muscle damage - Overdose= risk of bleeding
28
Vitamin D3: sources, function, deficiency, toxicity. What is D2
-D2= ergocalciferol. Derived from ergosterol in plants,, fungi and moulds. - D3= cholecalciferol. milk and dairy products. And formed in the skin by the action of UV light on 7-dehydrocholesterol. - Maintains calcium and phosphate levels in blood so bone mineralisation is achieved. - Deficiency= rickets, delayed tooth eruption, hypoplasia of enamel in children. osteomalacia in adults. - Toxicity= hypercalcemia, GI disturbances, calcification of heart, lungs, kidney.
29
Vitamin K: sources, function, deficiency signs, oral effects
- green leafy veg. Small amounts in milk, meat, eggs, cereals - used in blood clotting. Activates prothrombin. Funnels calcium into bones - deficiency = bruising easily, bleeds in mucous membranes - supports enamel mineralisation. And causes osteocalcin to produce dentine
30
Iron: sources, function, deficiency, oral relevance, absorption
- In Haemoglobin and myoglobin - In red meat, lentils, pulses, cocoa, curry powder, wholemeal bread, fortified cereals - Involved in oxygen transport - Deficiency causes anaemia. Early deficiency causes thinking of oral mucosa, a white film may loosen from the oral mucosa - Absorption from food is low but is increased by vitamin C
31
Calcium: sources, function, deficiency, absorption,
- dairy products- fortified white flour, fish with bones, watercress, dried figs, green veg - Component of bones, muscle contraction, nerve function, enzyme activity, blood clotting - Deficiency can lead to less dense bones and osteoporosis - Absorption= only 20-30% absorbed. Vitamin D is essential for absorption. Fibre and physic acid reduce absorption
32
Phosphorus: sources, function,
- dairy foods and marmite. - For healthy bones and teeth - utilisation of energy from food (ATP) nucleic acids - Present in all foods.
33
Magnesium: sources, function, excess
- Widespread in foods, especially green vegetables - Most is present in bones, present in enamel and dentine. - Essential in energy metabolism - Animal experiments have shown excess magnesium increases caries development. - Deficiency is rare.
34
Copper: sources, function, deficiency, requirements
- Functions in enzymes - Sources: Shellfish and liver, meat, bread, cereals and vegetables. - Deficiency: Menkys kinky hair syndrome! - Excess=Toxic - Present in saliva
35
Chromium: sources, function,
-Involved in glucose metabolism and widely distributed in foods.
36
Fluoride: , function,
-maintaining healthy bones and teeth
37
Iodine: function, sources
- Thyroid hormone constituent | - Seafood. Vegetables and cereals
38
Selenium: sources, function, high levels
- Antioxidant - Co-enzyme. - Found in animal protein. - High intakes provoke caries in experimental animals.
39
Zinc: sources, function,
-Immune function -Enzyme function -Present in bones -Sources: Meat and dairy Fibre reduces absorption.
40
What committee advises the government on the dietary reference values. What are DRVs and the eat well plate. What it doesn't take into consideration
- Scientific Advisory Committee on Nutrition (SACN) - DRVs are a series of estimated energy and nutrient requirements needed for different healthy populations (age, sex). - Reflected in the eat well plate: a visual representation of the proportions of each type of food needed in a balanced diet - Doesn't take into account activity levels for each individual, only for population groups
41
Difference between Reference nutrient intake (RNI), estimated average requirement(EARs) and Lower reference Nutrient Intake (LRNI). What they are all used for
1. RNI: the amount of a nutrient that allows 97.5% of the population to meet their needs - used as a reference amount for population groups, as 97.5% will be consuming the right amount. 2. EARs: average requirement for nutrient/ energy. So 50% of population will need less and the other 50% will need more - used for energy references (RNI not used as most people would be getting too much energy leading to obesity) 3. amount of nutrient that is only enough for 2.5% of population, who have low requirements. The rest of the population will need more. - useful measure of nutritional inadequacy.
42
What are the dietary reference values (%) for fat, saturated fat, trans FA, free sugar, protein, starch
- Fat <35% - Saturated fat <10% - trans fatty acid <2% - Free sugar <5% - Protein 12-15% -Starchy carbohydrates ~50%
43
What are the recommended amount of free sugar for 4-6 years, 7-10 years and 11+ years. (grams, cubes and teaspoons)
4-6 years =19g, 5 cubes, 4-5 tsp 7-10 years =24g, 6 cubes, 5-6 tsp 11+ =30g, 7 cubes, 6-7tsp
44
How many glasses of water a day is recommended. What are the average recommenced calorie intake for men and women. Portions of fish a week.
- 6-8 glasses of water a day - women= 2000kcal - men= 2500kcal - 2 portions of fish a week, 1 of which should be oily
45
What are wholegrain
- A whole grain is a grain of any cereal that contains the endosperm, germ, and bran, in contrast to refined grains, which retain only the endosperm - usually low in fat but rich in fibre and starchy carbohydrate and often have a low glycaemic index. - Also high in iron, magnesium, manganese, phosphorus - Eg. brown rice, oatmeal, barley, whole-wheat bread & pasta
46
What are good sources of protein
- Non dairy products | - Meat, fish, egg, beans, nuts