Theme C Flashcards
What are the analytical methods for collecting population research?
Trials - RCTS
What are the descriptive methods for collecting population research?
Survey
Case report
Case series
What are the observational methods for collecting population research?
Cohort
Case control
Describe a case control study
Observational
Begin with cases (people with the disease or outcome) and the controls (those without the disease or outcome)
Look into the past to look for risk factors or absence of risk factors
Describe cohort studies
Observational
Start with people who do not have the disease
Classify whether they are in the risk factor group or no risk factor
After a period of time look to see who has the disease / outcome
What are the problems associated with observational studies?
Confounding
Bias
What are some of the problems with measuring diet?
Random error
Homogeneity of exposure
Bias
Confounding
How can you measure diet?
Food disappearance data (national level)
Household surveys
Individual surveys
(24 hour recall, food frequency, diet diary, bio markers)
Pros and cons of diet diaries
Records diet as eaten
More flexible
Better estimate of energy and absolute intake
Requires effort to complete
Expensive to code
Alters diet while diary completed
What is internal validity?
Extent to which a causal conclusion based on the study is warranted.
Extent to which a study minimises systematic error
What is external validity?
Extent to which the results of the study can be generalised to other situations and other people
What can limit the generality of study findings?
- Situational specifics e.g. time, location, researcher, extent of measurement, treatment administration
- Pretest - if cause effect relationship are only found in pretest
- Post test - if cause effect relationship are only found in post test
- Reactivity - if effects only ocurred as an effect of studying the situation
- Rosenthal effects - inferences about cause-consequence relationships may not be generalisable to other researchers
Why do we need evidence based medicine?
Increasing medical knowledge Limited time to read Inadequacy of traditional sources Disparity between diagnostic skills/ clinical judgement Can improve medical practice
What are the four components for an evidence based decision?
Evidence from research
Clinical expertise
Patient preference
Available resources
What are the different types of research study?
Cohort Case control Randomised control trias Qualitative approaches Diagnostic and screening studies Systematic reviews
What is a cohort study appropriate for?
Prognosis
Cause
What is a case control study appropriate for?
Cause
What is a RCT appropriate for?
treatment interventions
benefits and harm
cost effectiveness
What is a qualitative study appropriate for?
Patients and/or practitioners perspective
What is the process for evidence based medicine?
- Convert the need for information into an answerable questions
- Identifying best evidence to answer that question
- Understanding it
- Critically appraising evidence for validity, impact and applicability
- Integrating critical appraisal with clinical expertise, patient circumstances and service constraints
- Evaluating effectiveness of steps 1-5
What is a background question?
General knowledge about a disorder
Who/what/where/when…. disorder
What is a foreground question?
Specific knowledge about managing patients with a disorder
Patient/problem
Intervention
Comparison intervention
Clinical outcomes
What is the control of communicable diseases based on?
Surveillance
Preventative measures
Outbreak investigation
Appropriate control measures
What are the host factors that influence infection?
Age Gender Alcoholism Drug abuse Co-existing diseases Port of entry Immuno-state Nutrition Genetic make up Cell receptors
Define outbreak
An epidemic limited to localised increase in the incidence of disease e.g. village, town
Define epidemic
The occurrence in a community or region of cases of an illness, specific health related behaviour, or other health related events clearly in excess than normal expectancy
Define pandemic
An epidemic occurring over a very wide area, crossing international boundaries and usually affecting a large number of people
Define surveillance
Systemic collection, collation and analysis of data and dissemination of the results so that appropriate control measures can be taken
What happens in outbreak investigation and control?
- Establish existence of outbreak and verify diagnosis
- Identify and count cases or exposure
- Time, place, person
- Formulate hypothesis and test
- Additional studies
- Evaluate control measures through surveillance
- Communicate findings
Define health care associated infections
Are those arising as a result of health care interventions, either in patients undergoing these interventions or in healthcare workers involved in interventions
What are the factors affecting the risk of acquiring a health care associated infecton?
Underlying disease Extremes of age Breach of defence mechanisms Exposure to infection Hospital pathogens Antibiotic resistance
What is the incidence of health care associated infections?
9% of in patients
1 billion per year costs
15,000 deaths a year
What are the common sites of hospital infections?
GI 22% Respiratory 20% Urinary tract 19% Surgical site 13% Skin 10% Blood stream 6%
What prevention strategies are part of the infection control programme?
- Advisory service
- Surveillance of hospital associated infections
- Detection investigation and control of outbreaks
- Policies and procedures to prevent infection
- Dissemination and implementation of national policy
- Education and training
- Monitoring clinical practice
What are some of the current policies and procedures for infection control?
- Screening of patients (MRSA)
- Barrier nursing-isolation of infected patients
- Sharp disposal
- Sterilisation and decontamination of instruments
- Procedures for use of medical devices
- Hand washing
- Hand sanitiser stations
What are the objectives of vaccinations?
Protect individuals from specific disease
Protect populations
What is the vaccination goal?
To reduce mortality and morbidity from vaccine preventable infections
What are the aims of vaccines?
Selective protection of vulnerable Eradication Elimination Prevent deaths Prevent infection Prevent transmission Prevent clinical cases
Who is included in a susceptible population (vaccination)?
- Any person who is not immune to a particular pathogen and is said to be susceptible
- A person may be susceptible because they have never encountered the infection or vaccine against it before
- A person may be susceptible because are unable to amount an immune response
- A person may be susceptible because vaccination is contraindicated for them
What is Ro?
Ro is the average number of secondary infections produced by a typical infective agent in a totally susceptible population
Ro does not fluctuate in short term, is not affected by vaccination and is a property of the infectious agent
What does Ro depend on?
Bug characteristics:
Infectivity of organism
Duration of infectiousness
Population characteristics:
Demographics
Population density
What is R?
Effective reproduction number
Average number of secondary infections produced by a typical infective agent
In a homogenously mixing population, where s is the proportion susceptible
R= Ro x s
How do mass vaccination programmes impact the disease?
Reduce the size of susceptible population Reduce number of cases Reduce risk of infection on population Reduce contract of susceptible to cases Lengthening of epidemic cycle Increase mean age of infection
What is the epidemic threshold?
R = 1
What happens if R>1?
Number of cases increases
What happens if R<1?
Number of cases decreases
What is required to eliminate a disease?
R<1
What is herd immunity?
Level of immunity in population which protects the whole population because the disease stops spreading in the community
Why is herd immunity important?
Only way to effectively eliminate an infection
Will never achieve 100% personal protection with vaccination
Less than 100% vaccine efficacy
Less than 100% vaccine uptake
How do you calculate critical vaccination coverage?
H = herd immunity threshold s* = critical proportion susceptible
H = 1-s*
How is vaccine efficacy calculated?
VE = vaccine efficacy AR = attack rate
VE% = AR (unvaccinated) - AR (vaccinated) x 100
What factors determine whether a disease is a burden?
Number of cases
Morbidity
Mortality
What effects how much a disease will be prevented?
Age-specific burden in relation to age of immunisation
Vaccine effectiveness
Likely coverage
Indirect effects of immunisation on disease transmission
What are the possible negative effects of the vaccine programme?
Risk from vaccine
Programme errors
Interference with existing strategys
What needs to be taken into account when implementing a new vaccine?
- Is the disease a public health problem?
- Are there other ways to control the disease?
- Impact of new vaccine
- Vaccine safety
- Vaccination schedule
- How much disease will be prevented?
- Side effects?
- Additional resources required
- Cost effectiveness
How do you implement a new vaccination program?
Pilots e.g. Hib in Gambia
Phased introduction e.g. pneumococcal UK
Global vaccination e.g. small pox
When do you vaccinate?
- Most likely to maximise uptake e.g. term time in school ages
- Greatest impact on disease burden e.g. seasonal diseases
- Use of multiple vaccines
When choosing the strategy for vaccination, what do you need to consider?
- Risk of exposure
- Risk of disease/complication
- Susceptibility
- Vaccine features (safety, side effects, efficacy)
- Acceptability/ timing issues
Why is international collaboration of vaccination necessary?
- Inequity in access to immunisation services
- Low political commitment and under investment in some countries
- Higher costs of service delivery
- Lack of commercial incentives for manufacturers to develop vaccines
- Some countries can’t guarantee vaccine quality
What are the elements of academic research?
Theory
Techniques
Methodology
Define epistemology
A theory of knowledge and knowledge production
e.g. where does knowledge come from and who has it
Define methodology
The practice and process of doing research including the role of the researcher
Define method
A technique or gathering date
e.g. questionnaire, interview, documentary analysis
Define positivism
A way of thinking that considers the social world and can be observed and studied using the methods of physical sciences
Researcher - value free, objective and neutral
Define interpretivism
Considers that the social world consists of multiple, subjective realities
Social interaction is studied in its natural surroundings
Researcher acknowledges their influence on the process through reflexivity
Define bad news
Any news that drastically and negatively alters the patient’s view of his or her future
What can clinicians worry about when delivering bad news?
- Uncertainty about patient expectations
- Fear of destroying patients hope
- Fear of their own inadequacy
- Not feeling prepared to manage patients emotional reactions
- Embarrassment having previously painted an optimistic picture
What are some of the distancing strategies used when breaking bad news?
Avoidance Normalisation Premature reassurance False reassurance Switching Jollying along
How should bad news be broken?
Advance preparation Build a relationship Communicate well Deal with patient reactions Encourage and validate emotion
OR
Setting up Perception Invitation Knowledge Emotions Strategy and summary
How should you deal with anger?
Recognise someones anger
Don’t dismiss it
Remain calm
What is risk transition?
As a country develops, the disease that affect the population shift from primarily communicable (infectious) to primary non-communicable
Improvements in medial care
Aging population
Public health interventions
What is primary prevention?
Aims to reduce exposure
What is secondary prevention?
Aims to identify those with pre-clinical disease to influence progression of disease
What is tertiary prevention?
Aims to modify outcomes of disease
What are the most common cancers in males?
Prostate
Lung
Bowel
What are the most common cancers in females?
Breast
Lung
Bowel
What cancers have the highest mortality?
Lung Bowel Breast Prostate Pancreas
What are the most common cancers occurring in children?
Leukaemia Brain tumour Neuroblastoma Lymphoma Retinoblastoma
What is the lifetime incidence of cancer?
1 in 3
What percentage of people die from cancer?
1 in 4
25%
How many people each year die of cancer?
270,000
What are some of the potential causes of UK poor performance in cancer treatment?
Differences in data collection Age differences Differences in stage of presentation Differences in social class Differences in access to treatment
What are the conclusions and consequences of the Eurocare-2 report?
Cancer survival in 80s and 90s was one of the worst in Europe
Expert Advisory Group formed in 1995 - Calman-Hine report
What was advised in the Calman-Hine report?
- All patients to have access to a uniformly high quality of care
- Public and professional education to recognise early symptoms of cancer
- Patients, families and carers should be given clear information about treatment options and outcomes
- The development of cancer services should be patient centred
- Primary care should be central to cancer care
- The psychosocial needs of cancer sufferers and carers to be recognised
- Cancer registration and monitoring of outcomes essential
What are the Calman-Hine solutions?
3 levels of care
- Primary care
- Cancer units serving DGHs (250,000)
- Cancer centres serving population in excess of one million
Why do we have MDTs with cancer treatment?
- Modern management of cancer involves many disciplines
- Allied health professionals e.g. nurses, physiotherapists, speech therapists etc. play an important role
- Delivery of cancer care is often fragmented over several hospital sites
- Better outcomes for patients managed in MDTs
Who is involved in an cancer care MDT?
Physician Surgeon Oncologist Radiologist Histopathologist Specialist nurse MDT co-ordinator Physiotherapist Dietician Palliative care Chaplain
What is the function of an MDT in cancer care?
- discuss every new diagnosis of cancer within their site
- decide on management plan for every patient
- inform primary care of that plan
- designate a key worker for that patient
- develop referral, diagnosis and treatment guidelines for their tumour sites according to local and national guidelines
- Audit
What strategy was developed to tackle cancer?
NHS Cancer plan (2000)
What are the aims of the NHS cancer plan?
- To save more lives
- To ensure people with cancer get the right professional support and care as well as the best treatments
- To tackle the inequalities in health (unskilled workers twice as likely to die from cancer)
- Build for a future through investment in cancer work force, through strong research and through preparation for the genetics revolution
What are cancer networks?
Organisational model for cancer services.
Serve 1-2 million
Brings together health services
What are the activities of a cancer network?
- Development of strategic plans
- Implementation of national policies
- delivery of improvements in the care of patients with cancer
- coordinate and support network activityies in relation to the pathway of patients within a specific tumour site
- Provides resources to enable network audits and research
- Provide a channel for communication across partners within the network
What were the 6 areas for action in the cancer reform strategy?
- Prevention
- Earlier diagnosis
- Ensuring better treatment
- Living with cancer and beyond
- Reducing cancer inequalities
- Delivering care in the most appropriate setting
What are the 4 key drivers for delivery of cancer care?
- Using information to drive quality and choice
- Stronger commissioning
- Funding world class cancer care
- Planning for the future
What is the purpose of critical reflection?
- Develop skills in life-long learning
- develop self-awareness with regards to attitudes, beliefs and values
- develops skills in understanding, analysing and questioning your practice and experiences
- understand and evaluate perspective of others
- identify strengths, weaknesses and training gaps
What is ethical reasoning?
The process of critical evaluation of ethical and legal aspects
Why is ethical reasoning important?
- understand and evaluate arguments
- know when to protest or challenge other people behaviour or practice
- make the right decisions as doctors
- explain and justify decisions that you make
- make decisions that you are able to live by and justify to yourself
What is a moral argument?
Argument that seeks to support a moral claim of some kind
What are the functions of the clinical record?
- Provide a record of patient’s contact with health care providers
- Act as an aide memoire and facilitate communication with and about patients
- Primarily they exist to support patient care
- Contains information useful for clinical audit, financial planning, management and research aimed at improving patient care in the future
- Range of social purposes at the request of patients
- To inform many people
- Support method and structure to history and examination
- ensure clarity of diagnosis
- enable structure and comprehensive monitoring
- Maintain consistent explanation for the patient
- ensure continuity of care
What is the contents of clinical records?
- Presenting symptoms and reasons for seeking health care
- Relevant clinical findings and diagnosis
- Options for care and treatment discussed with patient
- Risk and benefits of care
- Decisions about care and treatment including evidence of patients agreement
- Action taken and outcomes
What are the differences in the clinical record in primary and secondary care?
Primary - patient oriented, paper light, low tech content, correspondance rich
Secondary - imaging heavy, paper oriented, disease oriented
What is the law and policy on maintaining clinical records?
GMC - Clear, accurate, legible and contemporaneous patient records
What are the principles of the Data Protection Act 1998? (8)
- Personal data shall be processed fairly and lawfully
- Personal data shall be obtained only for one or more specified lawful purposes
- Personal data should be adequate, relevant and not excessive in relation to the purpose for which they are processed
- Personal data shall be accurate and kept up to date
- Data should not be kept for longer than necessary
- Processed in accordance with rights under the act
- Measures shall be taken against unauthorised processing and against destruction or damage
- It should not be transferred
What are the objective of NHS connecting for health?
- to improve patient choice and the quality and convenience of care
- ensure that clinicians have the right information at the right time to deliver care
- to deliver 21st century IT support for a modern, efficient NHS
Why is the body a problem?
- Bodies are sacred
- They cannot be treated the same as other objects
- They are the seat of the soul or the self
What is a body dysmorphic disorder?
A mismatch between inside and outside
Subjective and objective body image
What are the positive ways in which medicine changes bodies/
Plastic surgery for scarring
Re-constructive surgery
Drug treatments for skin conditions
What are the negative ways in which medicine changes bodies?
Drug side affects e.g. Thalidamide
Cosmetic surgery problems
Reproduction techniques
What are the types of body transtitions?
Ageing Accident/injury scars Hair loss Cancer Diabetes Lupus Menopause Pregnancy Skin disorder Stroke
What are the disadvantages of screening?
May face difficulty with - employment - insurance Ethical issues - passing on disorder to chidren
What are the advantages of diagnosis?
- Immediately life saving
- MDT support
- Bridge to transplantation
- Relieves loneliness and isolation
- Opportunity for further social involvement
What are the impacts of dialysis?
- Often have multiple medical problems
- Frequent hospital admissions
- Depression and psychological illness common
- Heavy burden on time (travel and clinics)
- Limitation of travel because of treatment
- Restrictions on fluid intake and diet
- Employment difficulties
- Cost to health provider
What is screening?
The systematic application of a test or inquiry to identify individuals at sufficient risk OR risk of a specific disorder to warrant further investigation or direct preventative action amongst people who have not sought medical attention
What level of prevention is screening?
Most is secondarY
Why should we screen?
- Opportunities for primary prevention are limited
- Opportunities for treatment are limited
- Screening gives potential for early and more effective treatment
When screening what is required from the condition?
- Important health problem
- Natural history of the condition should be understood e.g. should be a detectable risk factor and latent period
- Cost effective primary prevention should have been impletmented
When screening, what is required from the test?
- Simple, safe, precise, validated test
- Distribution of test values should be known
- Suitable cut off point agreed
- Test should be acceptable
- Agreed policy on further management
When screening, what is required from the treatment?
- effective treatment
- evidence that earlier treatment gives better outcomes
- clinical management of condition should be optimised prior to screening programme
When screening, what is required from the programme?
- RCT evidence that the programme is effective in reducing mortality or morbidity
- evidence that the whole programme is acceptable to professionals and public
- Benefit should outweigh harm
- Opportunity cost of programme should be economically balanced in relation to health care spending
- Plan for quality assurance
What is length bias?
Screening over-represents less aggressive disease
overestimation of survival benefit due to the detection of slowly growing lesions by screening tests, perhaps including lesions that will never cause mortality.
What is the consequence of length bias?
- Disease with a longer sojourn are easier to catch in the screening net
- Individuals with disease detected by screening automatically have a better prognosis than those who present with symptoms
- If you only compare individuals that chose to be screened against those who didn’t - distorted view
What is lead time?
Length of time between detection of a disease and its usual presentation and diagnosis
What is lead time bias?
bias that occurs when two tests for a disease are compared, and one test diagnoses the disease earlier, but there is no effect on the outcome of the disease
May appear to prolong survival but only diagnosed earlier
What is the consequence of lead time bias?
Survival is inevitably longer following diagnosis through screening because of the extra lead time
Appropriate measure of effectiveness is lost
What is good about “good” screening?
Early detection of disease means the risk of death or illness can be reduced in some people
What is bad about “good” screening?
Some people get tests, diagnosis and treatment with no benefit
Some people get ill or die despite a negative screening test
What are the relevant considerations for reproductive ethics?
- Interests of parents, procreative autonomy
- Interests of future child, welfare based
- Interests of third parties, including the state
What is assisted reproductive technology?
Any treatment or procedures involving in vitro handling of human oocytes and sperm or embryos for the purpose of achieving pregnancy
What are the ethical objections to the use of IVF?
- Involves destruction of embryos - some think that they have a moral status
- Harmful for those trying to conceive - risk of mortality and morbidity and loss success rate
- Unnatural - poor argument
What are the chance of success of IVF?
32% under 35 27% = 35-37 21% = 38-39 13% = 40-42 5% = 43-44 2% = 45+
What is the right to an open future?
Children will have a maximally open future.
Sometimes used to justify not allowing a selection of embryos that will grow into persons with serious disablities
What is the Human Fertilisation and Embryology Act 1990?
A woman will not be provided with fertility treatment services unless account has been taken of the welfare of any child who may be born as a result of the treatment
- Supportive parenting (2008)
Why is the welfare criterion in ART criticised?
- Might be unfair as unfertile couples do not have to meet this criterion
- Predicting the welfare of children is very difficult
- Research suggests that a father is not always required for a child to flourish
What IVF is available for those aged 23-39 on the NHS?
Up to 3 cycles on the NHS
What is PGD?
Screening of cells from implantation preimplantation embyros for detection of genetic or chromosomal disorders before embryo transfer
What are the uses of PGD?
Avoid genetic disease
Sex selection
Saviour siblings
What are the criteria to qualify for an abortion?
- less than 24 weeks
- Involve greater risk to continue the pregnancy - 3. Injury to physical or mental health of pregnant woman, existing children or family
- Termination prevents grave permanent injury to physical or mental health of woman
- Continuance would risk the life of the pregnant woman
- substantial risk that the child would suffer from physical or mental abnormalities
What is the pro-life argument?
Against abortion
- Abortion ends the life of a foetus
- Human foetus has moral status of a person
- Wrong to end a persons life
- Abortion morally wrong
What are the views of the moral status of a foetus?
- Identify as a human organism
- The potential to be a person
- Identity as a person
- Conferred moral status
What are the methods used to study drug safety?
Animal experiments Clinical trials Epidemiological methods - Spontaneous reporting - Post marketing surveillance - Cohort studies - Case control studies Meta-analysis
What is an adverse event?
An unintended event resulting from clinical care causing patient harm
What is a near miss event?
A situation in which events or omissions, arising during clinical care fail to develop further, whether or not as the result of compensating action, thus preventing injury to a patient
What is the iceberg model of errors?
- Misadventure - death/sever harm
- No harm event - potential for harm is present
- Near miss - unwanted consequences were prevented because of recovery
Only see actual harm, can miss the true scale of errors
Name some examples of adverse events in healthcare?
Wrong site surgery Medication errors Pressure ulcers Wrong diagnosis Failure to treat Patient fa Hospital acquired infection Medicine adverse effects
How many adverse events are heir in the NHS hospital sector per year?
850,000
What are the causes of serious obstetrics adverse events?
- Mismanagement of forceps-assisted delivery
- Inadequate supervision by senior staff
- Senior staff not recognising gravity of a problem
- Poor record keeping
- Onset of labour not correctly diagnosed
- Mothers not moved into delivery suite in time
- Inadequate foetal heart monitoring
- Signs for foetal distress missed or ignored
What was outlined in the Berwick report?
- The quality of patient care should be above all else
- Patient safety problems exist throughout
- Improvement requires system of support
- Patient and carers need to be engaged and empowered at all times
- Usually systems, procedures, conditions, environment and constraints and NOT STAFF that lead to safety incidents
What are the solutions of the Berwick report?
- Wide systemic change
- Abandon blame as a tool
- Work with patients and carers to achieve health care goals
- Use quantitative targets with caution
- Ensure responsibility for functions related to safety
What is the Keogh Review?
- Assessing patient safety needs hard data and soft intelligence
- Safety processes are often in place but not understood, therefore not implemented
- Findings of patient safety investigations need to be widely shared
- The at risk population needs to be easily identified and flagged
What are HSMR?
Hospital standardised mortality ratios
Why can comparing Hospital standardised mortality ratios be misleading?
- Random variation
- Definitions and coding
- Case mix (over adjustment and under adjustment of risk)
- Variations in planned place of death
- Relationship with quality of care
What percentage of deaths is preventable?
5.2%
12,000 deaths per year
What are the causes of adverse events?
- Active failure (focuses on errors of individual at frontline)
- System failure (concentrates on conditions under which an individual works)
- Equipment failure (when equipment is maintained and used appropriately)
What is the Swiss Cheese Model?
- Every step in a process has the potential for failure
- An error may allow a problem to pass through one layer
- The other layers act as a defence
- Each layer is a defence against potential error impacting outcome
What is an active failure?
Unsafe acts committed by people in direct contact with patient
- Usually short lived
- Often unpredictable
Errors or violations
What are the 3 types of errors?
Knowledge based
Rule based
Skills based
What is a skills based error?
Attention slips and memory lapses. Involved the unintended deviation of actions from what may have been a good plan
What is a rule-based error?
Encounter relatively familiar problem but apply the wrong rule .
Misapplication of good rule or application of a bad rule
What is a knowledge based error?
Forming wrong plans as the result of inadequate knowledge or experience
What are violations?
Deliberate deviations from a regulated code of practice or procedure. They occur because people break the rules intentionally
What are the 5 types of violations?
Routine Optimising Situational Reasoned Malicious
What is a routine violation?
A violation that has become normal behaviour within a peer group
What is an optimising violation?
The motive is to improve a work situation (e.g. in boring or repetitive job)
What is a situational violation?
Context dependent e.g. time pressure or low staffing level
What is a reasoned violation?
Deliberate deviation from protocol thought to be in the patient best interest at the time
What is a malicious violation?
Deliberate act intended to harm someone or the organisation
What is a latent error?
Develop over time and lay dormant until they combine with other factors or active failures to cause an adverse event
- Long lived
- Can be identified and removed before they cause an adverse event
- Training of staff
- Working environmental conditions
What is the blame culture?
Individuals cover up error for fear of retribution
Reduces focus on true causes of failure because of the emphasis on individual actions at the expense of the role of underlying systems
NHS is an example
What is the human factors approach?
Acknowledges the universal nature of human fallibility and the inevitability of error
Assumes that errors will occur
Designs things in the workplace to try to minimise the likelihood of error or its consequence
What situations are associated with an increased risk of error?
*Unfamiliarity with a task
*Inexperience
Shortage of time
Inadequate checking
Poor procedures
Poor human equipment interface
- especially with lack of supervision