Theme 4 - Dr. Robinson Flashcards

1
Q

What is homeostasis and what is it’s significance?

A

The same, standing or stopping. The significance is to maintain a steady internal environment.
Biochemical reactions are sensitive to changes in temp, pH, [solute], water, and pressure.

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2
Q

(Internal/external) cells are protected by fluids in homeostasis

A

Internal cells

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3
Q

What does extracellular fluid do?

A

Connects all cells to the external environment

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4
Q

What are the 7 factors of the internal environment that are homeostatically regulated.

A
  1. Temperature
  2. [water and NaCl] (cell volume)
  3. Vol and pressure of blood vessels
  4. [ ] of waste chemicals
  5. [O2 and CO2]
  6. pH
  7. Nutrient [ ] for NRG production by cells
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5
Q

What are the 4 homeostasis topics and their definitions

A
  1. Osmoregulation (regulation of internal osmotic (water/salt/waste) environment
  2. Circulation (bulk flow of fluid within the body (water, solutes, nutrients, gases)
  3. Gas Exchange (exchange w/ environment)
  4. pH regulation (controlling the [proton H+] of body fluids
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6
Q

What does bulk transport use in osmoregulation?

A

Hydrostatic pressure

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7
Q

In osmoregulation, how is diffusion specified?

A

Fick’s Law
Diffusion Rate = D A dC / dX

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8
Q

Why is osmosis important to animal cells?

A

Cells will shrink or swell if not maintained isosmotic

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9
Q

Why is osmosis important to plant cells?

A

Cells will develop turgor pressure as water enters, which limits further influx of water

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10
Q

What are osmoconformer strategies?

A

Adjust osmotic strength of cells [Y] and extracellular fluid [X] to match environment [Z]
Marine inverts, hagfish, elasmosbranchs

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11
Q

What are osmoregulator strategies?

A

Adjust osmotic strength of extracellular fluid [x] to match cells [Y] and protect the internal environment from the external [Z]
Freshwater inverts and most vertebrates

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12
Q

What is hyper osmotic? What type of environment is hyper osmotic?

A
  • Lose water to and gain self from the environment
  • Eliminate salt and consume, produce, conserve water
  • Limit salt intake
    (Marine environments)
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13
Q

What is hyposomotic? What type of environment is hyposmotic?

A
  • Gain water from and lose salt to the environment
  • Eliminate water and consume/conserve salt
  • Limit water intake
    (Freshwater environments)
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14
Q

What is excretion?

A

Elimination of waste/toxins, aids in controlling content of extracellular fluid (salt/water/pH)

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15
Q

What are the 3 steps of excretion as a mechanism for osmoregulation?

A
  1. Filtration (non-selective)
  2. Secretion (selective)
  3. Reabsorption (selective)
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16
Q

How do aquatic organisms excrete ammonia? (NH3)

A
  • Diffusion into the environment (across body/gills)
  • Excretion in filtrate/urine
  • Ammonium (NH4) / sodium exchangers
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17
Q

How do Terrestrial organisms excrete ammonia (NH3)?

A
  • Cannot use diffusion or ion exchange
  • Only excretion in filtrate
  • Produce urea
  • Produce uric acid (animals that develop in eggs)
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18
Q

What are osmoregulatory challenge adaptations for migratory salmon?

A

Fresh water -> Marine -> Fresh water
- Ion exchangers on gills
-Kidneys

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19
Q

What are osmoregulatory challenge adaptations for Marine Mammals?

A

No access to fresh water
- No gills
- lose little water by evaporation
- Gain by eating food and metabolic water

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20
Q

Why circulate fluids?

A

Processing of pH, osmolarity, waste, nutrients, and gas exchange.
Transportation of hormones, heat, gases, nutrients, immune components, solute

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21
Q

Why do smaller organisms not need circulatory systems?

A

Diffusion is adequate for small organisms. Larger animals need circulation.

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22
Q

What is an open circulatory system?

A

Open system has no distinction between hemolymph and interstitial fluid

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23
Q

What is a closed circulatory system?

A

Closed system has blood separated from interstitial fluid.

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24
Q

What are the 5 points of circulation in animals?

A
  1. Heterotrophs with digestive system
  2. High metabolic rates demand rapid circulation
  3. Flexible tubes
  4. Cardiovascular system is a muscular pump and vessels
  5. Can be open or closed
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25
What does extracellular fluid contain?
1. Plasma 2. Erythrocytes (carry gases) 3. Leukocytes (White blood cells) 4. Platelets
26
What makes up plasma? What are they key types of each?
- Water, ions, proteins, nutrients, and gases. Key ions: Na, K, Cl, HCO3, Ca, H Key Proteins: Globulins, albumin, fibrinogens Key Gases: O2 and CO2
27
What is Ohm's Law?
flow = Pressure / Resistance
28
What are blood vessels important for?
Transportation Storage Exchange
29
What are the functions of arteries?
- Carry fluid away from the heart - Control blood distribution to the body by controlling vessel diameter - Depulsate pressure waves from the beating heart
30
What are the functions of veins?
- Carry fluid back to the heart - Store blood
31
What are the functions of capillaries?
- Exchange of substances between blood and tissues - Promote diffusion
32
What are the 3 main reasons gas exchange is needed?
1. Krebs cycle / Oxidative Phosphorylation 2. Photosynthesis 3. pH regulation
33
What does breathing involve?
Bulk flow between the respiratory medium (air/water) and the gas exchange surface (body surface/lungs/gills)
34
Surface area of gas exchange is proportional to what?
Mass and metabolic rate
35
How does circulation move ECF?
Using the muscular heart and the blood vessels via bulk flow
36
Diffusion is based on pressure gradients. What does Partial gas pressure mean?
Each gas exerts a pressure It is proportional to its relative abundance in the mixture
37
What are the 3 patterns of gas exchange?
1. Countercurrent 2. Crosscurrent 3. Uniform pool
38
What is the orientation of water and blood flow that allows for a change in gradient over the gill?
If water and blood move in the same direction
39
What is the orientation of water and blood flow that allows for the gradient to be maintained over the gill?
If water and blood move in opposite directions
40
How does countercurrent exchange allow for heat retention?
Blood moved down arteries away from the heart where the body temperature is 37 degrees, and as it moves to the extremities, heat is lost to surrounding environment as well as to neighbouring veins. As the blood moves from the extremities up towards the heart from via veins, it gradually heats up as it nears the core.
41
What is the difference between open and closed circulatory systems?
In open circulation, the blood is not contained in the blood vessels, and is pumped into a cavity (hemocoel). In a closed system, the blood is pumped through blood vessels separate from interstitial fluid in the body.
42
How does blood move through a single circuit circulation system?
Blood flows through the heart only once during one cycle of passage through the body (2 chambered heart). Blood will pass through the heart to gills, then after purification, blood is distributed.
43
How does blood move through a double circuit circulation system?
Blood passes through the heart twice per circuit. the right pump sends deoxygenated blood to the lungs where it becomes oxygenated and returns back to the heart. The left pump sends the newly oxygenated blood around the body.
44
How does blood move through a variable circuit circulation system?
Unsure yet
45
What is the formula for pH?
-log10[H+]
46
How does pH affect proteins?
Alters charge Changes Shape Affects solubility, function, and enzymatic activity
47
What does Acid-Base regulation involve?
Production, retention, and removal of H+
48
What is the pulmonary buffering system and what is it's rate?
Ventilation (Plasm CO2) - minutes
49
What is the renal buffering system and what is it's rate?
Excretion/diffusion of HCO3 or H+ - hours to days
50
What is chemical buffering and what is it's rate?
Blood plasma - fast
51
What are buffers in blood plasma?
Human blood contains a buffer of carbonic acid and bicarbonate anion in order to maintain blood pH between 7.35-7.45
52
How does hyperventilation affect blood pH?
Breathing in excess of metabolic needs means expelling more carbon dioxide than is produced, resulting in respiratory alkalosis and an elevated blood pH.
53
What is contained in blood plasma?
Protein buffers Haemoglobin Bicarbonate-carbonic acid NH3
54
Why is homeostasis important?
Roles of osmoregulation, circulation, gas exchange, pH
55
What is osmoregulation?
Bulk flow, diffusion, and osmosis/water potential Osmoconformers and osmoregulators Water balance in terrestrial, marine, and freshwater environments Excretory organs, osmoregulation and metabolic waste (Ammonia excretion)
56
Why is gas exchange needed?
Krebs cycle and oxidative phosphorylation consume oxygen and produce CO2 - Photosynthesis consumes CO2 and produces O2 - pH regulation via CO2 regulation, forms carbonic acid
57
Explain ventilation by bulk flow (1)
Breathing moves air containing O2 into the lungs and air containing CO2 out of the lungs
58
Explain Diffusion across the respiratory surface (2)
Oxygen diffuses from the lung into the blood and CO2 diffuses out of the blood into the lungs
59
Explain Circulation by bulk flow (3)
Oxygen and carbon dioxide are transported by the circulatory system to and from cells
60
Explain Diffusion between blood and cells (4)
Oxygen diffuses from the blood into the cells and carbon dioxide diffuses out of the cells and into the blood
61
What does respiration do?
Regulates blood levels of carbonic acid
62