The Top 100 drugs

Question 1

Suggest 3 common indications for the use of Acetylcysteine

Answer 1

1. Antidote for paracetamol overdose
2. Help prevent AKI as a result of contrast nephropathy
3. Reduce viscosity of respiratory secretions

Question 2

What 3 tests are used to monitor acetlycysteine administration

Answer 2

1. INR
2. ALT
3. Creatine concentration

Question 3

Suggest 3 potential contra-indications to the administration of activated charcoal

Answer 3

1. Reduced GCS
2. Persisten vomiting
3. Reduced GI motility

Question 4

What is the indication for the use of adenosine?

Answer 4

Diagnosis and treatment of SVT (supraventricular tachycardias)

Question 5

Name 2 aldosterone antagonists

Answer 5

1. Spironolactone

2. Epleronone

Question 6

Give 3 common indications for the use of an aldosterone antagonist

Answer 6

1. Ascites and oedema due to liver cirrhosis
2. Chronic heart failure
3. Primary hyperaldosteronism

Question 7

What is Stevens-Johnson syndrome?

Answer 7

A T cell mediated hypersensitivity reaction

Question 8

Give 3 contra-indications for the use of aldosterone antagonists

Answer 8

1. Severe renal impairment
2. Hyperkalemia
3. Addison’s disease

Question 9

Which 2 potential side effects of high dose aldosterone antagonists are important to communicate to men before commencing a treatment regime?

Answer 9

1. Growth and tenderness of tissue under the nipples i.e. gynaecomastia
2. Impotence

Question 10

Suggest 3 common indications for the use of allopurinol

Answer 10

1. Prevent acute episodes of gout
2. Prevent uric acid/ calcium oxalate renal stones
3. Prevent hyperuricaemia and tumour lysis syndrome associated with chemotherapy

Question 11

What is the mechanism of action of allopurinol?

Answer 11

Xanthine oxidase inhibitor

Question 12

Suggest 2 common indications for the use of alpha blockers

Answer 12

1. First line symptom management of benign prostatic hyperplasia
2. Add on treatment in the management of resistant hypertension

Question 13

Name 3 alpha blockers

Answer 13

1. Doxazosin
2. Tamsulosin
3. Alfuzosin

Question 14

Suggest 3 adverse affects commonly associated with alpha blockers

Answer 14

1. Postural hypotension
2. Dizziness
3. Syncope

Question 15

Give an example of an aminoglycoside

Answer 15

Gentamicin

Question 16

Suggest 4 indications for the use of an aminoglycoside

Answer 16

1. Severe sepsis
2. Pyelonephritis
3. Biliary/ other intra abdominal sepsis
4. Endocarditis