the sympathetic nervous system Flashcards

1
Q

function of α1 receptors?

A
  • smooth muscle contraction
  • vasoconstriction
  • mydriasis
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2
Q

function of α2 receptors?

A
  • inhibition of neurotransmitter release
  • GI relaxation
  • inhibition of insulin release
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3
Q

function of ß1 receptors?

A
  • cardiac effects (positive inotropic, chronotropic)
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4
Q

function of ß2 receptors?

A
  • vasodilation
  • bronchodilation
  • uterus relaxation
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5
Q

function of ß3 receptors?

A

lipolysis in fat tissue

no products available

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6
Q

non-specific sympathomimetic drugs?

A
  1. Adrenaline (ß1 and ß2)
  2. Noradrenaline (ß1 and α1)
  3. Dopamine (effects dose dependant)

low dose (D1 receptors)

medium dose (ß1 receptors)

high dose (α1 receptors)

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7
Q

ß - receptor agonists?

A
  • dobutamine (mainly ß1)
  • isoproterenol (ß1 and ß2)
  • ß2 agonists
    • clenbuterole
    • salbutamole (doping)
    • salmererole
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8
Q

indications of ß agonists?

A
  • Horse RAO
  • Feline asthma
  • bronchitis, bronchopneumnia
  • trachea hypoplasia
  • tracheal collapse
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9
Q

α adrenoceptor agonists?

A

mainly α1 receptors - vasoconstriction

  • napthazoline
  • xylometazoline
  • phenylpropanolamine
  • Ephedrine
  • amphetamine
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10
Q

which α1 receptor agonist is used in the treatment of urinary incontinence?

A

Phenylpropanolamine (Propalin*)

urinary bladder sphincter constriction

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11
Q

α2 agonists?

A
  • Xylazine
  • detomidine
  • medetomidine
  • romifidine
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12
Q

Non - specific α -antagonists (sympatholytics)

A
  • Phenyoxybenzamine
  • phentolamine
  • tolazoline
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13
Q

what drug is used for urethral sphincter relaxation?

A

Phenoxybenzamine

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14
Q

α 1 antagonists

A
  • Prazosine
  • doxasazine
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15
Q

α 2 antagonists

A
  • Yohimbine
  • antipamezole
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16
Q

what drugs are considered antidotes for α 2 agonists?

A

α 2 antagonists

17
Q

Non specific ß antagonists

A
  • Propanolone
  • Timolole
18
Q

specific ß1 antagonists?

A
  • metroprolone
  • atenolol
19
Q
A