the sympathetic nervous system Flashcards
function of α1 receptors?
- smooth muscle contraction
- vasoconstriction
- mydriasis
function of α2 receptors?
- inhibition of neurotransmitter release
- GI relaxation
- inhibition of insulin release
function of ß1 receptors?
- cardiac effects (positive inotropic, chronotropic)
function of ß2 receptors?
- vasodilation
- bronchodilation
- uterus relaxation
function of ß3 receptors?
lipolysis in fat tissue
no products available
non-specific sympathomimetic drugs?
- Adrenaline (ß1 and ß2)
- Noradrenaline (ß1 and α1)
- Dopamine (effects dose dependant)
low dose (D1 receptors)
medium dose (ß1 receptors)
high dose (α1 receptors)
ß - receptor agonists?
- dobutamine (mainly ß1)
- isoproterenol (ß1 and ß2)
- ß2 agonists
- clenbuterole
- salbutamole (doping)
- salmererole
indications of ß agonists?
- Horse RAO
- Feline asthma
- bronchitis, bronchopneumnia
- trachea hypoplasia
- tracheal collapse
α adrenoceptor agonists?
mainly α1 receptors - vasoconstriction
- napthazoline
- xylometazoline
- phenylpropanolamine
- Ephedrine
- amphetamine
which α1 receptor agonist is used in the treatment of urinary incontinence?
Phenylpropanolamine (Propalin*)
urinary bladder sphincter constriction
α2 agonists?
- Xylazine
- detomidine
- medetomidine
- romifidine
Non - specific α -antagonists (sympatholytics)
- Phenyoxybenzamine
- phentolamine
- tolazoline
what drug is used for urethral sphincter relaxation?
Phenoxybenzamine
α 1 antagonists
- Prazosine
- doxasazine
α 2 antagonists
- Yohimbine
- antipamezole