The Skeletal System Flashcards
How many bones is the skeletal system composed of?
206 bones
How many bones is the axial skeleton composed of?
80 bones of the skull, spine, ribs & sternum
How many bones is the appendicular skeleton composed of?
126 bones of the extremities, pectoral, and pelvic girdles
What are the five types of bones?
Long, short, irregular, flat, sesamoid
What type of tissue is bone?
connective
What are bones covered with (outer layer)?
Periosteum
What is the inner layer of bones made up of?
Osteoblasts
What are osteoblasts associated with?
The production of bone
What is beneath the inner layer of periosteum?
Cortial or compact bone
What is below the cortical layer of bone?
The cancellous or spongy bone (honeycomb appearance)
What is the name of the open canal that runs down the center of the diaphysis (shaft) of long bones and contains the bone marrow?
Medullary or marrow cavity
What lines the marrow cavity?
Endosteum
What are the two types of tissue found in the cavities of bones?
Red bone marrow and yellow bone marrow?
Where is the red bone marrow found and what is its function?
It is found in the open areas of spongy bone and forms red blood cells
Where is the yellow bone marrow found and what is its function?
Yellow bone marrow contains predominantly fat and is found in the marrow cavity of long bones
What are the three types of joints?
Synarthrodial, amphiarthrodial, and diarthrodial
Synarthrodial joinst are
immovable
Amphiarthrodial joints are
slight movable
Diarthrodial joints are
freely movable
What is ossification?
The process of bone replacing fibrous membranes and begins with the appearance of osteoblasts
What are osteoblasts?
Bone-forming cells
What do osteoblasts form?
Bone matrix
What are osteoclasts?
Cells associated with the absorption and removal of bone. They “eat away” the inside of the marrow cavity white the osteoblasts build up the outside of the bone
What are the main functions of the skeletal system?
Support, protection, movement, production of blood cells, & storage
What is scoliosis?
Lateral deviation and rotation of the spine
What are the various types of scoliosis?
Idiopathic, congenital, or acquired
What is congenital scoliosis commonly the result of?
hemivertebrae, wedge vertebrae, or neuromuscular development
What is wedge vertebrae or hemivertebrae?
A failure of formation of the vertebrae
What is the most definitive and important diagnostic tool for scoliosis?
Imaging
What are other modalities used to image scoliosis?
CT, MRI, ultrasound (prenatally), & nuclear medicine when patient presents with pain
What is a transitional vertebrae?
A vertebrae that takes on the characteristics of the vertebrae on either side of it
What is CDH?
Congenital dislocated hip also known as development dysplasia of the hip
What happens with CDH?
the capsule of the hip joint relaxes and allows dislocation of the hip
Who is affected the most by CDH?
Caucasian females
What percentage of newborns showing clinical signs of CDH will revert back to normal after 6 to 8 weeks of age?
75%-95%
What complications may take place if CDH is not diagnosed and treatment is not put into place?
Avascular necrosis, a possibility of pseudoacetabulae, and secondary osteoarthritis will occur later in life in the 50s or 60s
What is spina bifida?
The failure of fusion of one or more vertebral arches
What is spina bifida occulta (SBO)?
Occurs when the two halves of the posterior arch fail to unite
What is the most common location of SBO?
The first sacral vertebra
In SBO, what happens with the spinal cord?
There is no protrusion of the spinal cord or its membrane, however if neural elements project through the defect without any meninge covering, a myelocele is present
What is Meningocele?
When a cerebrospinal fluid (CSF) filled sac is covered with the meninges of the cord
What happens with spina bifida aperta?
There is a wide bony defect in the posterior arch of the lumbar vertebrae
What is myelomeningocele?
A sac containing CSF and some of the neural elements of the cord protruding
What modalities are used to diagnose myelocele, meningocele, and myelomeningocele
Sonography as early as 12 weeks, plain radiographs, and MRI
What is Osteogenesis imperfecta?
An inherited connective tissue disorder that affects multiple organs and not just the skeletal system
What is another name for osteogenesis imperfecta?
brittle bone disease because of the extreme vulnerability of bones to fracture
What are the two types of osteogenesis imperfecta?
Congenital and tarda
What is there a lack of with osteogenesis imperfecta?
There is a lack of osteoblastic activity and abnormal collagen formation so that the skeleton does not ossify properly
How many people does OI affect?
Between 20,000 and 50,000 people in the United States with 1 in every 20,000 births being afflicted
Is congenital or tarda more severe in regards to OI?
Congenital
What happens to infants with congenital OI?
They are stillborn or die very early
What happens to the long bones in individuals with OI?
The long bones are short, thick, and bowed, resembling dwarfism
When does the tarda form appear in regards to OI?
After puberty with multiple fractures and milder deformities of the long bones at varying times following birth
What is often associated with osteogensis imperfecta?
deafness since the small ossicles can easily fracture
What is the most common and mildest form of OI?
Type 1 (OI tarda 1)
What is the most severe form of OI?
Type IV
What is used to determine the initial diagnosis of OI?
Dual-energy X-ray absorptiometry
What appears on radiographs in individuals with OI?
diffuse osteoporosis with thin cortices, short and thick extremities, and a narrow pelvis
What happens to technique in patients with OI?
The kVp must be increased slightly because fractures heal by producing more bone
What process is exactly opposite of OI?
Osteopetrosis
What is osteopetrosis?
a deficiency of osteoclasts and therefore, faulty bone absorption
What is another name for osteopetrosis?
Marble bone disease
What are the different forms of osteopetrosis?
Osteopetrosis infantile, osteopetrosis tarda, and osteopetrosis intermediate
What happens with osteopetrosis infantile?
Frequently ends in blindness and deafness and then death by age of 2 years
What happens with osteopetrosis tarda?
It remains asymptomatic with detection being made with anemia or pathologic fractures
What happens with osteopetrosis intermediate?
It falls somewhere in between the other two forms
Patients who suffer from osteopetrosis are prone to what?
Osteomyelitis
What modalitiy is the best diagnostic procedure when diagnosing osteopetrosis?
Radiography and is supported by CT
What happens to your technique when imaging patients with osteopetrosis?
With such a high increase in density of the bones, the technical factors will need to be increases. The kVp will need to be increased but not above 75 for extremities, as the scatter will be greater.
What is achondroplasia?
The failure of the cartilage that becomes bone to form properly, thus not allowing ossification to proceed as it should
What is achondroplasia caused by?
An abnormal gene located on one of the chromosomes
What disease is the most common cause of disproportionate short stature occurring in 1 in 15,000 to 1 in 25,000 live births?
achondroplasia
Who is most affected by achondroplasia?
it occurs in all races and both sexes
What is are physical signs of an individual with achondroplasia?
They have short extremities while the trunk and skull are of normal size. Often the arms are shorter than the lower extremities. Lordosis of the lumbar spine, bowed legs, and a bulky forehead with a saddle shaped nose. Nasal passages are narrowed and the jaw is small so that the teeth may be crowded and poorly aligned
What happens to the technique when radiographing an infant with achondroplasia?
because the cartilage is not ossified as it should, radiographs will not require the higher kVp settings
What is osteopenia?
A nonspecific radiographic finding that indicates increased radiolucency of bone
What are the two types of osteopenia?
Osteoporosis and osteomalacia
What is osteoporosis?
When osteoblasts fail to lay down sufficient amount of bone matrix, an abnormal decrease in bone density occurs
What are the prime factors associated with osteoporosis?
Age, gender, race
Who is affected most by osteoporosis?
Occurs more often in women and among Whites and Asians than in African Americans
What are the different variety of clinical conditions osteoporosis may occur in?
Secondary and primary
What is more common, primary osteoporosis or secondary?
Primary (not associated with underlying cause)
What are some of the common locations of osteoporosis?
Spine, pelvis, hips, femurs, distal radius/hand, and proximal humerus/shoulder
What do radiographs show when imaging people with osteoporosis?
Lack of density in the bones die to loss of calcium and thin cortices with fewer trabeculae
What happens to technical factors when imaging an individual with osteoporosis?
Technical factors (particularly kVp) should be decreased so as mot to overexpose the image and cause a repeat radiograph
What is the best modality for osteoporosis?
DEXA
What is osteomalacia?
It is an abnormal decrease in bone caused by a lack of calcium and phosphorus. This leads to softening of the bone in an adult.
What is a cause of osteomalacia?
Vitamin D deficiency and pregnancy
If osteomalacia occurs before the growth plate at the epiphysis closes in children, what is it called?
Rickets
What is another name for rickets?
Infantile osteomalacia
What is a common manifestation in Rickets?
Bowing of the legs
What are other radiographic signs in individuals with osteomalacia?
Generalized reduction in bone density due to decreased number of trabeculae
What is osteodystrophy?
A disturbance in the growth of bone due to lack of vitamins
What are a few causes of osteodystrophy?
Lack of vitamins and renal failure
Brown tumors are associated with what?
Osteodystrophy
What are brown tumors caused by?
Large amounts of osteoclasts that “eat” away the inside of the bone, causing a lesion
What does increased osteoclastic activity result in?
Subperiosteal bone resorption
What disease is characterized by lace-like patterns of the outer cortex of the digits, femur, and humerus?
Osteodystrophy
What disease is associated with radiographic images with a fuzzy, moth-eaten appearance of the skull known as the “salt and pepper” skull?
Osteodystrophy
When renal osteodystrophy occurs in the spine, what is it called?
A “rugger jersey spine”
What is osteomyelitis?
Infection of the bone and bone marrow
What is osteitis?
Infection of only the bone
What is osteitis mostly caused by?
Staphylococci bacteria carried through the blood, but it can also be caused directly if bacteria enter the bone from outside due to conditions such as a compound fracture
What is the usual site for development of osteomyelitis?
Long bones of the lower limbs
What happens when osteomyelitis occurs and inflammation causes a rise in pressure within the bone , but the periosteum constricts buildup causing the vessels in the bone to become compressed?
The bone will die within 24 to 48 hours
What is dead bone called?
Sequestrum
What does dead bone cause on a radiographic image?
It causes a linear opacity
What is Osteitis deformans or Paget disease?
Overproduction of bone
What kind of disease is Osteitis deformans or Paget disease?
Idiopathic disease