The RAAS

Question 1

Renin is secreted from

Answer 1

kidneys - when they detect a decrease in renal perfusion (low BP)

Question 2

Renins affect on BP

Answer 2

RAISES

Question 3

Angiotensinogen is secreted from

Answer 3

liver

Question 4

ACE is secreted from

Answer 4

surface of pulmonary and renal endothelium

Question 5

Angiontensin II affect on BP

Answer 5

increases BP

Question 6

The 5 actions of angiotensin II

Answer 6

Increases sympathetic activity
Increases tubular Na+, water and Cl- reabsorption, and K+ excretion
Stimulates aldosterone secretion from adrenal cortex
Arteriolar vasoconstriction
ADH secretion from posterior pituitary gland (increases water re-absorption in CD)

Question 7

Affect of aldosterone

Answer 7

Increasing BP
Via increasing reabsorption of Na+, water, Cl- and K+ excretion in the collecting duct (increases synthesis of channels)
Increases synthesis of Na/Cl symporter in the DCT of nephrons

Question 8

ADH is synthesised in

Answer 8

hypothalamus

Question 9

ADH is secreted from

Answer 9

posterior lobe of pituitary gland

Question 10

What do renal prostaglandins do?

Answer 10

dilate the renal afferent artery

stimulate renin release from juxtaglomerular cells in the afferent arteriole

Question 11

What does renin act on?

Answer 11

Converts angiotensingen from the liver into angiotensin I