The Neuron Flashcards

1
Q

Nervous system

A

system of neurons

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2
Q

Two components of the nervous system and what they contain

A

Central Nervous System

  • brain
  • spinal cord

Peripheral Nervous system
-Nerves & Nerve Cells outside the brain and spinal cord.

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3
Q

What is so special about neurons

A

they have an excitable membrane, and they could signal over long distances.

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4
Q

What are the tree parts of the neuron

A

the dendrites, the cell body (soma), axon

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5
Q

What characteristics do vertebrates have?

A

brain, and segmented spinal cord.

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6
Q

What are the two major cell types found in the central nervous system and what do they do?

A
  • neurons–>transmit information
  • Glial cells (*astrocytes
  • oligodendrocytes)–> support neurons, modulate neuronal activity, development, clean up.
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7
Q

What is the difference between Gray matter and white matter?

A

Gray Matter consists primarily of neuronal cell bodies (soma).

White matter consists of myelinated axons, whitish in color due to their high lipid fat content.

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8
Q

where is Gray vs White Matter found?

A

In the brain (cerebrum and cerebellum) white matter is predominately found in deeper areas–with gray matter coating the white matter.

In the spinal cord, things are largely reversed and the white matter is distributed around the central gray matter.`

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9
Q

Neurobiology

A

the study of how the cells of the brain and nervous system control behavior

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10
Q

Santiago Ramon y Cajal

A
  • known as “the father of neuroscience” (the original brain mapper)
  • wanted to be an artist, but parents forced him to go to medical school
  • Really got into drawing different neuron types,(particularly the cerebellar perkinje fibers) and DESCRIBED INFORMATION FLOW through neurons.

Scientists wanted to see detailed morphology of neurons and to be able to label them. But they were transparent and hard to see. Cajal labeled the neurons using the Golgi technique

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11
Q

The “Golgi Technique”

A

Cajal used the Golgi technique to label cells. This technique was developed my Camilo Golgi who was his rival, but they still shared the Nobel Prize in 1906.

Because of Cajal, we now can identify structures of neurons and their functions. His drawings are still used in textbooks today.

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12
Q

Who shared the Nobel prize in 1906?

A

Ramon y Cajal & Camilo Golgi.

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13
Q

What kind of neurons did Ramon Y Cajal identify?

A

local interneurons vs projection neurons, excitatory vs inhibitory neurons.

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14
Q

what is an interneuron?

A

Interneurons are the central nodes of neural circuits, enabling communication between sensory or motor neurons and the central nervous system (CNS). They play vital roles in reflexes, neuronal oscillations, and neurogenesis in the adult mammalian brain.

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15
Q

What is a projection neuron?

A

Broadly defined, projection neurons are neurons whose axons extend from the neuronal cell body within the central nervous system (CNS) to one or more distant regions of the CNS.

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16
Q

Excitatory neuron

A

class definition: (releases NT that INCREASES the activity of the target neuron)

online def.: An excitatory neuron is defined as a neuron that triggers a positive change in the membrane of a post synaptic neuron it connects to.

17
Q

Inhibitory neuron

A

class definition: (releases NT that DECREASES the activity of the target neuron.)

online def.: An inhibitory neuron triggers a negative change in the membrane of a post synaptic neuron it connects to.

18
Q

What is the difference between local interneurons versus projection neurons?

A

Local interneurons are in in close proximity and as the name implies “localized”, while projection neurons have long axons and project throughout the body.

19
Q

Cajal’s Law of Dynamic polarization

A

states that neurons are polarized, there is an input and output, and information flows from dendrite to axon.

20
Q

What does sub-threshold mean? and how do you signify it with in a circuit drawing?

A

a stimulus that is not strong enough to elicit a response. Below a threshold.

It is signified by using (+) inside or next to the neuron.

21
Q

The nervous system uses ______ to send “signals” through the nervous system.

A

electricity.

22
Q

what is the currency for electricity in the nervous system(and other cells)?

A

“charged ions”

  • NaCl –> Na + Cl-
  • KCl –> K + Cl-
23
Q

why does the nervous system use electricity?

A

~Because it can travel quickly
~It can travel long distances
~Can be very specific

24
Q

what is the fundamental key to neuron excitability?

A

a charged membrane potential.

25
Q

what is a membrane potential (Vm) ?

A

Membrane potential is the difference in electric potential between the interior and the exterior of a biological cell.

a potential is basically a difference in voltage across the cell membrane.

26
Q

what allows signals to propagate through the nervous system?

A

changes in the membrane potential.

27
Q

Neurons tightly control where the ________ ____ are, and when they move— this underlies signals.

A

charged ions